(n.) The quality or state of being irascible; irritability of temper; irascibleness.
Example Sentences:
(1) I learned that the hard way: when I was younger, I played the part of the erratic, irascible drunk in order to have something to write about.
(2) All round Europe there have been political earthquakes in a volatile anti-politics age: the surprise is that Britain’s scratchy, irascible electorate hasn’t expressed its underlying anger that ordinary people paid the price for the bankers’ crash.
(3) Kaczyński is behaving like Józef Piłsudski, the brilliant but irascible prewar leader who brought Poland back to independence in 1918.
(4) The mother is irascible, the father aloof; on the other hand, the parental combination "mother and father affectionate" is more common.
(5) The ability to be a good listener, unflappable and patient enough to deal with irascible family members, mediating family spats and calming ruffled feathers also helps.
(6) But she's not bad as the partner of an Iraq-bound soldier in Timeless: perhaps a bit plummier than you might expect a squaddie's wife required to live with her irascible great-grandmother in a tiny house to be, but certainly nothing like the disaster the world has come to expect from supermodels demonstrating their polymath abilities.
(7) Nancy's novels and Jessica's memoirs offered a beguiling - and friends thought - inaccurate picture of the extraordinary life lived out chez Mitford under the irascible gaze of Lord Redesdale ("Uncle Matthew" in Love in a Cold Climate), celebrated for his dislike of foreigners and his daughters' friends, disparaged collectively as "sewers".
(8) In 1959, he starred in Carol Reed's Our Man In Havana, and a year later gave a brilliantly unpleasant Scottish impersonation of an irascible soldier in Tunes Of Glory.
(9) Known for his irascibility, the writer has in one sense softened in late middle age.
(10) Now the Newsnight presenter Jeremy Paxman, famous for giving ruthlessly short shrift to politicians, has confirmed that his irascible on-screen attitude towards Westminster is more than skin deep.
(11) But his less enthusiastic answer about Bannon comes amid reports of infighting in the Trump White House, all of which place the gruff, irascible Bannon at the center.
(12) The clinico-pathological characteristics of the case were as follows: Fibrillary gliosis of the midbrain and pontine reticular formation corresponded clinically to personality changes: The patient had formerly been irascible and became extremely mild-mannered.
(13) All good knockabout stuff and the makings of a legend - irascible, menacing, self-important, egoistical.
(14) His father was an irascible, blind barrister, the Mortimer of Mortimer on Wills, Probate and Divorce.
(15) Yet, if you speak to some at Shirebrook, she seems to portray an image that can be as irascible as charming.
(16) Though more conservative in his politics, McAvoy, with his irascible personality and his unfortunate attitude to authority, is thought to be based on the former MSNBC news host Keith Olbermann, who quit the network after a very public falling-out, going then to the upstart Current TV channel, which he left in March this year after another row with the management.
(17) Typical Munchausen behaviors such as irascibility, the desperate search for care, and pseudologia fantastica, may be understood as solutions to problems created by brain damage.
(18) Wrestling with an opponent who will not recognise the prejudice in a phrase like "hideous Jewish face" had finally pushed Rampton, who cultivates a manner of curmudgeonly irascibility, into a foul mood.
(19) What is quickly turning into a public relations nightmare for the irascible Rodman – whose fellow players looked like they would rather be anywhere but Pyongyang during his tetchy pre-game interview with CNN on Tuesday – can only have helped burnish Kim's reputation, at least at home.
(20) It was an unexpected flash of humanity from this irascible stickler for social propriety.
Ire
Definition:
(n.) Anger; wrath.
Example Sentences:
(1) An insulin response element (IRE) has been identified in the prolactin gene using chimeric plasmids in which prolactin promoter DNA directs expression of the bacterial chloramphenicol acetyltransferase gene.
(2) The lability of the Fe-S cluster in mitochondrial aconitase has led us to propose that the mechanism by which iron levels are sensed by the IRE-BP involves changes in an Fe-S cluster in the IRE-BP.
(3) Government officials drew the public’s ire after charging Manning with three counts of misconduct following the suicide attempt, including two which carried possible penalties of indefinite solitary confinement.
(4) In a prospective, blinded trial, 40 healthy adult subjects using six IRED thermometers with two techniques were examined in random sequence.
(5) On Wednesday, the ire of the marchers was focused on all those Lib Dems who blithely signed the NUS's anti-fees pledge ("I pledge to vote against any increase in fees in the next parliament and to pressure the government to introduce a fairer alternative" – yesterday, Nick Clegg limply said that he "should have been more careful" than to put his name to it).
(6) Oleg Sentsov should make new films, not count years in prison.” Facebook Twitter Pinterest Oleg Sentsov sings the Ukrainian national anthem as he is sentenced to 20 years in a Russian penal colony Sentsov attracted the ire of the Russian authorities after helping to organise a campaign protesting at Russia’s occupation and annexation of Crimea in March 2014.
(7) A deletion and reconstitution study was undertaken to address the possibility that regions of the ferritin gene and mRNA other than the IRE may be necessary for the production of the full range of iron regulation.
(8) Her predecessor, Nick Robinson, attracted similar ire by upsetting Scottish nationalists .
(9) Interestingly, the FRP which remains active at a given hemin concentration binds to the IRE with the same high affinity as untreated FRP.
(10) The results strongly suggest that HCV RNA carries an internal ribosome entry site (IRES).
(11) Among the 17 pancreatic cancer patients with elevated IRE, 10 underwent radical resection of the cancer but in none of the five patients with normal serum IRE could radical resection be carried out.
(12) In addition, a poor sequence context around AUG-11 results in increased initiation at one or more downstream AUG codons, indicative of leaky scanning or jumping by the ribosome from AUG-11 mediated by the EMCV IRES.
(13) Amino acid alignments reveal that the IRE-BP is 30% identical to mitochondrial aconitase.
(14) Regulation in both instances is mediated by binding of a cytosolic protein to the IREs.
(15) Binding of the IRE-BP represses ferritin translation and represses degradation of the TfR mRNA.
(16) Yet in doing so it presents an angled mirror-polished cliff face of glass, which has been reflecting the sun straight across into the Lloyds offices across the road – the seminal "inside-out" machine that Rogers designed 30 years earlier – much to the ire of its tenants.
(17) The nations with the highest recorded levels include Colombia, Uganda, Afghanistan, India, Pakistan, Bangladesh and Nepal, with the south Asian countries in particular producing unforgettable images of disfigured women who have been assaulted with acid because they have rejected sexual advances or marriage proposals, or aroused jealousy, or in some way or other inconvenienced the patriarchy and aroused its ire.
(18) Artificial mono- and dicistronic mRNAs were prepared and used to identify the region that carried the IRES.
(19) Two melanotic human melanoma cell lines, IRE 1 and IRE 2, and the lymphoma- and leukaemia-derived cell lines Raji and K 562, were exposed to different concentrations (from 5 X 10(-3) M to 10(-5) M) of phenols, both substrates (s) and non-substrates (ns) of tyrosinase, in the presence or absence of the oxygen-radical-scavenger enzymes superoxide dismutase, catalase and peroxidase.
(20) Afterwards, she was "suddenly beautiful", and though the attention this brought was occasionally useful, mostly it was just a pain in the butt: the tiresome suggestions that she had only got on thanks to her appearance; the hurtful ire of that other great feminist, Betty Friedan, whose loathing of Steinem seemed mostly to be motivated by envy.