(1) An insulin response element (IRE) has been identified in the prolactin gene using chimeric plasmids in which prolactin promoter DNA directs expression of the bacterial chloramphenicol acetyltransferase gene.
(2) The lability of the Fe-S cluster in mitochondrial aconitase has led us to propose that the mechanism by which iron levels are sensed by the IRE-BP involves changes in an Fe-S cluster in the IRE-BP.
(3) Government officials drew the public’s ire after charging Manning with three counts of misconduct following the suicide attempt, including two which carried possible penalties of indefinite solitary confinement.
(4) In a prospective, blinded trial, 40 healthy adult subjects using six IRED thermometers with two techniques were examined in random sequence.
(5) On Wednesday, the ire of the marchers was focused on all those Lib Dems who blithely signed the NUS's anti-fees pledge ("I pledge to vote against any increase in fees in the next parliament and to pressure the government to introduce a fairer alternative" – yesterday, Nick Clegg limply said that he "should have been more careful" than to put his name to it).
(6) Oleg Sentsov should make new films, not count years in prison.” Facebook Twitter Pinterest Oleg Sentsov sings the Ukrainian national anthem as he is sentenced to 20 years in a Russian penal colony Sentsov attracted the ire of the Russian authorities after helping to organise a campaign protesting at Russia’s occupation and annexation of Crimea in March 2014.
(7) A deletion and reconstitution study was undertaken to address the possibility that regions of the ferritin gene and mRNA other than the IRE may be necessary for the production of the full range of iron regulation.
(8) Her predecessor, Nick Robinson, attracted similar ire by upsetting Scottish nationalists .
(9) Interestingly, the FRP which remains active at a given hemin concentration binds to the IRE with the same high affinity as untreated FRP.
(10) The results strongly suggest that HCV RNA carries an internal ribosome entry site (IRES).
(11) Among the 17 pancreatic cancer patients with elevated IRE, 10 underwent radical resection of the cancer but in none of the five patients with normal serum IRE could radical resection be carried out.
(12) In addition, a poor sequence context around AUG-11 results in increased initiation at one or more downstream AUG codons, indicative of leaky scanning or jumping by the ribosome from AUG-11 mediated by the EMCV IRES.
(13) Amino acid alignments reveal that the IRE-BP is 30% identical to mitochondrial aconitase.
(14) Regulation in both instances is mediated by binding of a cytosolic protein to the IREs.
(15) Binding of the IRE-BP represses ferritin translation and represses degradation of the TfR mRNA.
(16) Yet in doing so it presents an angled mirror-polished cliff face of glass, which has been reflecting the sun straight across into the Lloyds offices across the road – the seminal "inside-out" machine that Rogers designed 30 years earlier – much to the ire of its tenants.
(17) The nations with the highest recorded levels include Colombia, Uganda, Afghanistan, India, Pakistan, Bangladesh and Nepal, with the south Asian countries in particular producing unforgettable images of disfigured women who have been assaulted with acid because they have rejected sexual advances or marriage proposals, or aroused jealousy, or in some way or other inconvenienced the patriarchy and aroused its ire.
(18) Artificial mono- and dicistronic mRNAs were prepared and used to identify the region that carried the IRES.
(19) Two melanotic human melanoma cell lines, IRE 1 and IRE 2, and the lymphoma- and leukaemia-derived cell lines Raji and K 562, were exposed to different concentrations (from 5 X 10(-3) M to 10(-5) M) of phenols, both substrates (s) and non-substrates (ns) of tyrosinase, in the presence or absence of the oxygen-radical-scavenger enzymes superoxide dismutase, catalase and peroxidase.
(20) Afterwards, she was "suddenly beautiful", and though the attention this brought was occasionally useful, mostly it was just a pain in the butt: the tiresome suggestions that she had only got on thanks to her appearance; the hurtful ire of that other great feminist, Betty Friedan, whose loathing of Steinem seemed mostly to be motivated by envy.
Mire
Definition:
(n.) An ant.
(n.) Deep mud; wet, spongy earth.
(v. t.) To cause or permit to stick fast in mire; to plunge or fix in mud; as, to mire a horse or wagon.
(v. t.) To soil with mud or foul matter.
(v. i.) To stick in mire.
Example Sentences:
(1) For decades, resource extraction on First Nations land and chronically underfunded schools have left many of these communities mired in poverty, alcoholism and disease.
(2) Our computer-based corneal topography analysis system was used to study the keratoscope photographs (keratograms) from two patients with classic pellucid marginal degeneration and a third patient with no inferior corneal thinning, whose keratoscope mire pattern was suggestive of the condition.
(3) With an out-of-session Congress deadlocked over immigration reform and right-wing lawmakers hell-bent on “sealing the border”, the White House faces intense pressure to do something – anything – about immigration, after years of burying a civil rights crisis in a mire of political tone-deafness and jingoistic bombast.
(4) A leading thinktank has forecast that Britain will remain mired in recession this year, and slashed growth forecasts for almost all members of the G7 group of leading industrial nations.
(5) The European commission released a statement about the situation later on Wednesday, less than two weeks after agreeing a rescue deal for Greece that was meant to prevent Italy and Spain being dragged into the mire.
(6) The discovery of "serious failings" in the sale of these so-called interest rate swaps comes as the banking industry is mired in controversy about manipulating interest rates following the record-breaking £290m fine slapped on Barclays on Wednesday.
(7) Since the incumbent, Ilham Aliyev, inherited power from his late father 10 years ago, Azerbaijan has become mired in rampant corruption , and the ruling regime has grown ever more authoritarian and ruthless .
(8) The French president, François Hollande , will have 25 minutes on primetime television on Sunday evening to convince his nation that he will keep his election pledges and drag his country out of the economic mire.
(9) But I was wrong to peg Let’s Be Cops down in the mire with the Scary Movie franchise.
(10) Mired in a deepening recession, with the economy projected to shrink by at least 2.4% this year, Italy also posted more bad news, with retail sales figures for July showing a 3.2% fall on a year ago.
(11) Dismayingly, the elected government of the president, Ashraf Ghani, like that of Hamid Karzai before it, has proved incompetent, divided, and mired in corruption .
(12) Hunt also argued that the current "sink or swim system" in which free schools, academies and academy chains were managed by Whitehall, had left the school landscape mired in incoherence, confusion and lack of accountability.
(13) A government investigation into his death has become mired in controversy after a judge nominated to head the probe said he would not participate.
(14) The economy has been mired in recession for six consecutive quarters - the longest slump in history – but the CBI now expects output to grow by 1.2% in 2010 and by 2.5% in 2011.
(15) This is an attempt to increase choice and drive digital switchover, which is mired in difficulty but another key duty.
(16) Companies have cut staff and costs to the bone , but demand remains sluggish in the US, and Europe is still mired in a financial crisis of historic proportions.
(17) Her response on a Seattle cable channel to Barack Obama’s state of the nation address in January, in which she accused the president of betraying Americans mired in poverty , spread via the internet and reinforced her growing reputation among activists outside Seattle.
(18) The margin of victory was still a comfortable 95 runs, and the win lifts Warwicks well out of the relegation zone, while leaving Kent deeper in the mire.
(19) One small shareholder, who introduced himself as Captain Hawker, said BP had stepped into a “PR nightmare” by handing out such largesse when the rest of the country was mired in austerity.
(20) Last year 87% of the 900,000 migrants making the journey to Europe came through Greece but, following the European Union’s new deal with Turkey , smugglers’ gangs are already sizing up Libya – which is mired in the chaos of civil war – as an alternative route.