(1) An insulin response element (IRE) has been identified in the prolactin gene using chimeric plasmids in which prolactin promoter DNA directs expression of the bacterial chloramphenicol acetyltransferase gene.
(2) The lability of the Fe-S cluster in mitochondrial aconitase has led us to propose that the mechanism by which iron levels are sensed by the IRE-BP involves changes in an Fe-S cluster in the IRE-BP.
(3) Government officials drew the public’s ire after charging Manning with three counts of misconduct following the suicide attempt, including two which carried possible penalties of indefinite solitary confinement.
(4) In a prospective, blinded trial, 40 healthy adult subjects using six IRED thermometers with two techniques were examined in random sequence.
(5) On Wednesday, the ire of the marchers was focused on all those Lib Dems who blithely signed the NUS's anti-fees pledge ("I pledge to vote against any increase in fees in the next parliament and to pressure the government to introduce a fairer alternative" – yesterday, Nick Clegg limply said that he "should have been more careful" than to put his name to it).
(6) Oleg Sentsov should make new films, not count years in prison.” Facebook Twitter Pinterest Oleg Sentsov sings the Ukrainian national anthem as he is sentenced to 20 years in a Russian penal colony Sentsov attracted the ire of the Russian authorities after helping to organise a campaign protesting at Russia’s occupation and annexation of Crimea in March 2014.
(7) A deletion and reconstitution study was undertaken to address the possibility that regions of the ferritin gene and mRNA other than the IRE may be necessary for the production of the full range of iron regulation.
(8) Her predecessor, Nick Robinson, attracted similar ire by upsetting Scottish nationalists .
(9) Interestingly, the FRP which remains active at a given hemin concentration binds to the IRE with the same high affinity as untreated FRP.
(10) The results strongly suggest that HCV RNA carries an internal ribosome entry site (IRES).
(11) Among the 17 pancreatic cancer patients with elevated IRE, 10 underwent radical resection of the cancer but in none of the five patients with normal serum IRE could radical resection be carried out.
(12) In addition, a poor sequence context around AUG-11 results in increased initiation at one or more downstream AUG codons, indicative of leaky scanning or jumping by the ribosome from AUG-11 mediated by the EMCV IRES.
(13) Amino acid alignments reveal that the IRE-BP is 30% identical to mitochondrial aconitase.
(14) Regulation in both instances is mediated by binding of a cytosolic protein to the IREs.
(15) Binding of the IRE-BP represses ferritin translation and represses degradation of the TfR mRNA.
(16) Yet in doing so it presents an angled mirror-polished cliff face of glass, which has been reflecting the sun straight across into the Lloyds offices across the road – the seminal "inside-out" machine that Rogers designed 30 years earlier – much to the ire of its tenants.
(17) The nations with the highest recorded levels include Colombia, Uganda, Afghanistan, India, Pakistan, Bangladesh and Nepal, with the south Asian countries in particular producing unforgettable images of disfigured women who have been assaulted with acid because they have rejected sexual advances or marriage proposals, or aroused jealousy, or in some way or other inconvenienced the patriarchy and aroused its ire.
(18) Artificial mono- and dicistronic mRNAs were prepared and used to identify the region that carried the IRES.
(19) Two melanotic human melanoma cell lines, IRE 1 and IRE 2, and the lymphoma- and leukaemia-derived cell lines Raji and K 562, were exposed to different concentrations (from 5 X 10(-3) M to 10(-5) M) of phenols, both substrates (s) and non-substrates (ns) of tyrosinase, in the presence or absence of the oxygen-radical-scavenger enzymes superoxide dismutase, catalase and peroxidase.
(20) Afterwards, she was "suddenly beautiful", and though the attention this brought was occasionally useful, mostly it was just a pain in the butt: the tiresome suggestions that she had only got on thanks to her appearance; the hurtful ire of that other great feminist, Betty Friedan, whose loathing of Steinem seemed mostly to be motivated by envy.
Sire
Definition:
(n.) A lord, master, or other person in authority. See Sir.
(n.) A tittle of respect formerly used in speaking to elders and superiors, but now only in addressing a sovereign.
(n.) A father; the head of a family; the husband.
(n.) A creator; a maker; an author; an originator.
(n.) The male parent of a beast; -- applied especially to horses; as, the horse had a good sire.
(v. t.) To beget; to procreate; -- used of beasts, and especially of stallions.
Example Sentences:
(1) Sires of the cows had been divergently selected on yearling weight (YW) and total maternal (MAT) EPD to form four groups: high YW, high MAT EPD; high YW, low MAT EPD; low YW, high MAT EPD; and low YW, low MAT EPD.
(2) Beyond 20 mo, weights were adjusted to a constant condition score within breed of sire.
(3) Genetic parameters were estimated from sire components of variance and covariance obtained from a multiple-trait restricted maximum likelihood procedure.
(4) Simmental sires had significantly heavier calves at birth and S and H dams tended to have more calving difficulty and lower survival rates.
(5) Micromanipulation of sperm and ova has been suggested as a means to produce progeny of two sires instead of a sire and dam.
(6) Each sire family consisted of a sire, his foals, and the dams of those foals.
(7) Records of birth weight (BW), weaning weight (WW) and condition score (CS) from 1,467 Brahman and Brahman X Angus crossbred calves from Brahman and crossbred Brahman sires and Brahman, crossbred Brahman and Angus dams were collected at the Subtropical Agricultural Research Station, Brooksville, Florida, from 1971 to 1982.
(8) Live BW, carcass data, and organ data taken at 34 days of age on approximately 1,000 quail of both sexes from 110 sires and 290 dams were utilized to estimate genetic parameters from the initial generation of a selection study.
(9) Weaning weight records of 44,357 Australian Angus calves produced by 1,020 sires in 90 herds were used to evaluate the importance of sire x herd interactions.
(10) Additive relationships among sires and maternal grandsires were included.
(11) The purebred animals represented progeny of 107 sires.
(12) Repeatabilities and heritabilities of days to first service, days open, and number of services per conception were estimated from 235,589 records on 80,333 Holstein cows, daughters of 306 sires obtained from the Quebec Dairy Herd Analysis Service, by REML.
(13) Calves of mature dams were all sired by Limousin bulls and slaughtered at 12 mo.
(14) In single purpose dairy populations, sire models gave biased estimates of genetic parameters even when all data were included in the analysis.
(15) By including an artificial sire and an artificial dam and choosing appropriate merit values for the artificial matings, this problem can be solved by efficient "transportation" algorithms.
(16) A study of 24 offspring from one sire, heterozygous for W10 and Eu28R, showed that offspring inheriting Eu28R from the sire were significantly more likely to have antibodies to BLV than offspring inheriting the opposing W10 haplotype.
(17) Forty-three Hampshire or Suffolk-sired ram lambs were weaned at 60 d of age (average 23.6 kg of BW) and assigned to a 2 x 2 factorial arrangement of treatments consisting of 1) basal diet (control = BAS), 2) BAS with 6% whole canola seed (CS), 3) BAS with 4.9% deoiled soy lecithin (SL), and 4) BAS with 6% CS and 4.8% SL (CSSL).
(18) The correlation between sire of fetus effect and sire of cow effect on three production traits - milk yield, fat yield, and protein yield - in first lactation cows was investigated.
(19) Corresponding numbers of sires were 298, 289, 305, and 313.
(20) A sire-maternal grandsire mixed model with relationships was used to analyze the data to yield BLUP for the sire and maternal grandsire effects.