(n.) Blame; cause of blame; fault; crime; offense.
(n.) Deficiency; want; need; destitution; failure; as, a lack of sufficient food.
(v. t.) To blame; to find fault with.
(v. t.) To be without or destitute of; to want; to need.
(v. i.) To be wanting; often, impersonally, with of, meaning, to be less than, short, not quite, etc.
(v. i.) To be in want.
(interj.) Exclamation of regret or surprise.
Example Sentences:
(1) Here we have asked whether protection from blood-borne antigens afforded by the blood-brain barrier is related to the lack of MHC expression.
(2) tRNA from mutant IB13 lacks 5-methylaminomethyl-2-thio-uridine in vivo due to a permanently nonfunctional methyltransferase.
(3) BL6 mouse melanoma cells lack detectable H-2Kb and had low levels of expression of H-2Db Ag.
(4) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(5) In the past, the interpretation of the medical findings was hampered by a lack of knowledge of normal anatomy and genital flora in the nonabused prepubertal child.
(6) A diplomatic source said the killing appeared particularly unusual because of Farooq lack of recent political activity: "He was lying low in the past two years.
(7) The present study examined whether the lack of chronic hemodynamic effects of ANP in control rats was due to changes in vascular reactivity to the peptide.
(8) Since it was established, it has stoked controversy about contemporary art, though in recent years it has been more notable for its lack of sensationalism.
(9) Inadequate treatment, caused by a lack of drugs and poorly trained medical attendants, is also a major problem.
(10) Because of the small number of patients reported in the world literature and lack of controlled studies, the treatment of small cell carcinoma of the larynx remains controversial; this retrospective analysis suggests that combination chemotherapy plus radiation offers the best chance for cure.
(11) I would immediately look askance at anyone who lacks the last and possesses the first.
(12) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(13) Core enzyme, lacking omega subunit, catalyzed this reaction at a rate less than 1% that of holoenzyme.
(14) But not only did it post a larger loss than expected, Amazon also projected 7% to 18% revenue growth over the busiest shopping period of the year, a far cry from the 20%-plus pace that had convinced investors to overlook its persistent lack of profit in the past.
(15) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(16) Thus the failure to raise anti-Id with internal image characteristics may provide an explanation for the lack of anti-gp120 activity reported in anti-Id antisera raised to multiple anti-CD4 antibodies.
(17) His walkout reportedly meant his fellow foreign affairs select committee members could not vote since they lacked a quorum.
(18) In South Africa, health risks associated with exposure to toxic waste sites need to be viewed in the context of current community health concerns, competing causes of disease and ill-health, and the relative lack of knowledge about environmental contamination and associated health effects.
(19) The functional capacity to present antigens to T cells was lacking in normal resting B cells, but was acquired following LK treatment.
(20) These findings indicate an association between HLA-B7 and ankylosing spondylitis in American blacks and suggest that these patients who lack B27 but possess B7 represent a subgroup of patients with this disease.
Lock
Definition:
(n.) A tuft of hair; a flock or small quantity of wool, hay, or other like substance; a tress or ringlet of hair.
(n.) Anything that fastens; specifically, a fastening, as for a door, a lid, a trunk, a drawer, and the like, in which a bolt is moved by a key so as to hold or to release the thing fastened.
(n.) A fastening together or interlacing; a closing of one thing upon another; a state of being fixed or immovable.
(n.) A place from which egress is prevented, as by a lock.
(n.) The barrier or works which confine the water of a stream or canal.
(n.) An inclosure in a canal with gates at each end, used in raising or lowering boats as they pass from one level to another; -- called also lift lock.
(n.) That part or apparatus of a firearm by which the charge is exploded; as, a matchlock, flintlock, percussion lock, etc.
(n.) A device for keeping a wheel from turning.
(n.) A grapple in wrestling.
(v. t.) To fasten with a lock, or as with a lock; to make fast; to prevent free movement of; as, to lock a door, a carriage wheel, a river, etc.
(v. t.) To prevent ingress or access to, or exit from, by fastening the lock or locks of; -- often with up; as, to lock or lock up, a house, jail, room, trunk. etc.
(v. t.) To fasten in or out, or to make secure by means of, or as with, locks; to confine, or to shut in or out -- often with up; as, to lock one's self in a room; to lock up the prisoners; to lock up one's silver; to lock intruders out of the house; to lock money into a vault; to lock a child in one's arms; to lock a secret in one's breast.
(v. t.) To link together; to clasp closely; as, to lock arms.
(v. t.) To furnish with locks; also, to raise or lower (a boat) in a lock.
(v. t.) To seize, as the sword arm of an antagonist, by turning the left arm around it, to disarm him.
(v. i.) To become fast, as by means of a lock or by interlacing; as, the door locks close.
Example Sentences:
(1) A bouncy function has now been incorporated into a knee of the semi-automatic knee lock design in a pilot laboratory trial involving six patients.
(2) The only other black woman I see in the building: washing dishes behind a door that was supposed to have been locked.
(3) In contrast, 1:1 phase locking characterized the electrical correlates of the duodenal activity front.
(4) When you hear the name Jesus, is the first image that comes to mind a dewy-eyed pretty boy with flowing locks?
(5) The commonly used line-to-line reaming technique was compared to an underreaming technique using both four-fifths and one-third porous-coated anatomic medullary locking (AML) implants.
(6) Andrew and his wife Amy belong to Generation Rent, an army of millions, all locked out of home ownership in Britain.
(7) While the Spielberg of popular myth is Mr Nice Guy, Lean was known as an obsessive, cantankerous tyrant who didn't much like actors and was only truly happy locked away in the editing suite.
(8) One top Republican official told the Guardian the party has for months been locked in secret talks with TV networks about how – or whether – it will fit all the candidates onstage for the primary debates.
(9) We develop an analogy between the steric hindrance among receptors detecting randomly placed haptens and the temporary locking of a Geiger counter that has detected a radioactive decay.
(10) On Wednesday, managing director Mike Devereux also flagged that the company's future in the country was not certain if government funding was not locked in over a long period.
(11) The violence led to the temporary suspension of the council's monthly meeting with some staff at one stage locked in rooms to ensure their safety.
(12) There have been reports of difficulties with the seating and locking of the vaporisers which can cause a leak and failure of vapour delivery.
(13) Such mutations lead to a major reduction in the rate of GTP hydrolysis by the complex of ras p21 and the GTPase activating protein (GAP) and lock the protein in a growth-promoting state.
(14) He was a fixture at Trump rallies, where he met chants of “Lock her up” against Hillary Clinton with a smile.
(15) No doubt New Labour ministers would regard such moves as protectionism, locked as they are in a discredited free-market mindset.
(16) So-called "structured" savings accounts promoted heavily by banks and building societies promise savers extra interest if they lock their money away for at least five years.
(17) Palmer sought to clarify his statements on Tuesday, and said they were aimed at the company he is currently locked in a dispute with, and not the broader Chinese population.
(18) Foveal exposures that did not produce an immediately visible lesion did not produce measurable changes in VEP response lock-in time.
(19) Scream Queens is the kind of show where you discover a secret locked room in the basement in one scene and then we find out exactly what is in the room three scenes later.
(20) In a group of the MS-DB units with stable background theta bursts the typical response consisting of entrainment of the phase-locked theta cycles was changed neither by physostigmine, nor by cholinergic-blocking drugs (scopolamine and atropine).