(3d pers. sing. pres.) of Last, to endure, contracted from lasteth.
(a.) Being after all the others, similarly classed or considered, in time, place, or order of succession; following all the rest; final; hindmost; farthest; as, the last year of a century; the last man in a line of soldiers; the last page in a book; his last chance.
(a.) Next before the present; as, I saw him last week.
(a.) Supreme; highest in degree; utmost.
(a.) Lowest in rank or degree; as, the last prize.
(a.) Farthest of all from a given quality, character, or condition; most unlikely; having least fitness; as, he is the last person to be accused of theft.
(a.) At a time or on an occasion which is the latest of all those spoken of or which have occurred; the last time; as, I saw him last in New York.
(a.) In conclusion; finally.
(a.) At a time next preceding the present time.
(v. i.) To continue in time; to endure; to remain in existence.
(v. i.) To endure use, or continue in existence, without impairment or exhaustion; as, this cloth lasts better than that; the fuel will last through the winter.
(v. i.) A wooden block shaped like the human foot, on which boots and shoes are formed.
(v. t.) To shape with a last; to fasten or fit to a last; to place smoothly on a last; as, to last a boot.
(n.) A load; a heavy burden; hence, a certain weight or measure, generally estimated at 4,000 lbs., but varying for different articles and in different countries. In England, a last of codfish, white herrings, meal, or ashes, is twelve barrels; a last of corn, ten quarters, or eighty bushels, in some parts of England, twenty-one quarters; of gunpowder, twenty-four barrels, each containing 100 lbs; of red herrings, twenty cades, or 20,000; of hides, twelve dozen; of leather, twenty dickers; of pitch and tar, fourteen barrels; of wool, twelve sacks; of flax or feathers, 1,700 lbs.
(n.) The burden of a ship; a cargo.
Example Sentences:
(1) These data indicate a steady improvement in laboratory performance over the last 10 years.
(2) City badly missed Yaya Touré, on international duty at the Africa Cup of Nations, and have not won a league match since last April when he has been missing.
(3) Future Brown have connections in the fashion industry, last year soundtracking a surreal film for the brand Telfar.
(4) "This is the third event in the last few days following An-26 and SU-25 planes being brought down.
(5) Peripheral vascular surgery has become an increasingly common mode of treatment in non-university, community hospitals in Sweden during the last decade.
(6) Michael Schumacher’s manager hopes F1 champion ‘will be here again one day’ Read more Last year, Red Bull were frustrated by Mercedes, Ferrari and Honda as they desperately looked for a new engine supplier.
(7) In each study, all subjects underwent four replications (over two days) of one of the six permutations of the three experimental conditions; each condition lasted 5 min.
(8) Mike Ashley told Lee Charnley that maybe he could talk with me last week but I said: ‘Listen, we cannot say too much so I think it’s better if we wait.’ The message Mike Ashley is sending is quite positive, but it was better to talk after we play Tottenham.” Benítez will ask Ashley for written assurances over his transfer budget, control of transfers and other spheres of club autonomy, but can also reassure the owner that the prospect of managing in the second tier holds few fears for him.
(9) All the patients told about a comfortable feeling of warmth after each treatment lasting for one two days.
(10) It comes in defiant journalism, like the story televised last week of a gardener in Aleppo who was killed by bombs while tending his roses and his son, who helped him, orphaned.
(11) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
(12) I would immediately look askance at anyone who lacks the last and possesses the first.
(13) David Cameron last night hit out at his fellow world leaders after the G8 dropped the promise to meet the historic aid commitments made at Gleneagles in 2005 from this year's summit communique.
(14) A new propaganda video by Islamic State featuring the British photojournalist John Cantlie, in which he says it is the “last film in this series”, has appeared online.
(15) Maternal diabetes and antihistamine use during the last 2 weeks of pregnancy were associated with significantly higher rates of retrolental fibroplasia, whereas toxemia was associated with lower rates.
(16) A review is presented concerning the development of new neuroimaging techniques in the last decade which have improved the diagnostic exploration of patients with spinal cord injuries, including studies of possible sequelae.
(17) The discussion on topics like post-schooling and rehabilitation of motorists has intensified the contacts between advocates of traffic law and traffic psychologists in the last years.
(18) Though the 54-year-old designer made brief returns to the limelight after his fall from grace, designing a one-off collection for Oscar de la Renta last year , his appointment at Margiela marks a more permanent comeback.
(19) In a Bloomberg article last week, for example, one Stanford student compared women who get raped to unlocked bicycles : ‘Do I deserve to have my bike stolen if I leave it unlocked on the quad?’ [Chris] Herries, 22, said.
(20) Mary's grief, which lasts for about the first half of the two-hour premiere special, is the finest work of the series so far by Michelle Dockery.
Lat
Definition:
(v. t.) To let; to allow.
Example Sentences:
(1) LATS was measured with the double isotope technique in IgG serum concentrates of 23 patients with Graves' disease before treatment and of 18 patients during treatment with carbimazole and triiodothyronine.
(2) More importantly, this study reports the first detection of LAT in RNA extracted from 9% of corneas from latently infected rabbits (n = 22) by the polymerase chain reaction.
(3) Conversely, MS patients, especially those in AF, appear to be at high risk of harboring an LAT.
(4) Out of 50 consecutive untreated patients with diffuse toxic goitre 15 showed long-acting thyroid stimulator (LATS), 30 showed LATS protector only, and five showed neither.
(5) VO2max and lactate threshold workload (LaT) of six subjects were assessed on a Monark ergometer.
(6) The number of herpes simplex virus (HSV) genome equivalents recovered from latently infected mouse spinal ganglia was compared with the proportion of neurons containing latency-associated transcripts (LATs).
(7) The serum levels of LATS and thyroid hormones were high.
(8) latex agglutination test (LAT), two indirect hemagglutination tests (IHAT) (Carter-Wallace, USA and Ismunit, Italy), enzyme immunoassay (EIA) and indirect fluorescent antibody test (IFAT).
(9) Using herpes simplex viruses deleted and restored for the latency-associated transcripts (LATs), we have quantitatively assessed the role of the transcripts in establishment and maintenance of latent infection.
(10) These results indicate that HSV-1 LAT expression is not an absolute requirement for establishment of the latent state.
(11) The cAMP-PDE activity in the thyroid significantly increased in both the LATS and TSH groups, but the cGMP-PDE activity was unchanged.
(12) Furthermore, LAT effectively inhibits transactivation of gene expression by infected-cell polypeptide 0 in transient transfection assays.
(13) We evaluated two LATs (Accu-Staph; Carr-Scarborough, Decatur, Ga.; Staphaurex; Wellcome, Dartford, England) with particular emphasis on their ability to correctly identify oxacillin-resistant S. aureus.
(14) There is strong evidence in favour of the hypothesis that lat molecules function as components of the T receptor for self Ia proteins in a I-restricted manner.
(15) Actually, positive rate in LAT was higher than that in DP among clinical specimens in which M. pneumoniae was detected by culture method.
(16) When 3-5 volumes of 0.5% Rivanol solution were mixed to serum containing TSH or LATS activity, LATS activity remained mainly with IgG in the supernatant fraction.
(17) All of these features of the LATs in humans are consistent with those reported in rabbits and mice and further validate the animal models of human HSV-1 infection.
(18) The long-acting thyroid stimulator (LATS) has been thought to be responsible for the hyperthyroidism of Graves's disease.
(19) Demonstration of LATS in the serum, slightly increased serum-triiodothyronine-levels, failure of normal response to TRH and an abnormal triiodothyronine-suppression test in euthyroid ophthalmopathy may herald the manifestation of hyperthyroidism at some later time.
(20) Most patients have elevated levels of LATS in their serum; however, this appears to be a marker for the disease, rather than a cause.