What's the difference between least and lest?

Least


Definition:

  • (a.) Smallest, either in size or degree; shortest; lowest; most unimportant; as, the least insect; the least mercy; the least space.
  • (adv.) In the smallest or lowest degree; in a degree below all others; as, to reward those who least deserve it.
  • (conj.) See Lest, conj.

Example Sentences:

  • (1) The most actively proliferating region of the excurrent duct system is zone 3 of the epididymis, whereas the least active region is the ductuli efferentes.
  • (2) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
  • (3) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
  • (4) These results show that the pathogenic phenotypes of MCF viruses are dissociable from the thymotropic phenotype and depend, at least in part, upon the enhancer sequences.
  • (5) These organic compounds were found to be stable on the sorbent tubes for at least seven days.
  • (6) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
  • (7) The patients should have received treatment for at least seven days and they should not be "ill".
  • (8) Extensive studies during recent years have shown that the interaction between hormone and membrane-bound receptor can affect the receptor characteristics in at least two ways.
  • (9) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
  • (10) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
  • (11) For his lone, perilous journey that defied the US occupation authorities, Burchett was pilloried, not least by his embedded colleagues.
  • (12) In 22 cases (63%), retinal detachment was at least partially flattened in the area of the posterior pole of the eye.
  • (13) An experimental Anaplasma marginale infection was induced in a splenectomized mule deer (Odocoileus hemionus hemionus) which persisted subclinically at least 376 days as detected by subinoculation into susceptible cattle.
  • (14) The family comprises at least three variable (V) gene segments, three constant (C) gene segments, and three junction (J) gene segments.
  • (15) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
  • (16) In vivo studies were performed in five healthy subjects for at least 3 h after ingestion of radiolabeled meals.
  • (17) Ryzhkov added: "I believe they want to keep him in prison for another three or four years at least, so he is not released until well after the next presidential elections in 2012."
  • (18) Patients served as their individual control based on observations of at least 1 year before the study.
  • (19) The reproducibility of the killing-curve method suggests that at least two different concentrations should be used and that a decrease in viable counts below 2 log10 after 24 hours does not exclude a synergistic action.
  • (20) She was not aware that it was an assassination attempt by alleged foreign agents.” If at least one of the women thought the killing was part of an elaborate prank, it might explain the “LOL” message emblazoned in large letters one of the killers t-shirts.

Lest


Definition:

  • (v. i.) To listen.
  • (n.) Lust; desire; pleasure.
  • (a.) Last; least.
  • (a.) For fear that; that . . . not; in order that . . . not.
  • (a.) That (without the negative particle); -- after certain expressions denoting fear or apprehension.

Example Sentences:

  • (1) The sexual rehabilitation of such patients is vital and must be done sensitively lest one's own concepts of "adequate sexuality" be imposed.
  • (2) But lest the duchess feel overlooked, the end section of the show featured long, pale-blue bias-cut crepe dresses with more of a charity gala feel; and knee-length silk crepe dresses with black grosgrain belts seemed princess friendly.
  • (3) Worse, the CFL contains mercury, which according to the EU's own regulations cannot be discarded in ordinary waste, lest the mercury leach into the water supply.
  • (4) And lest there be any remaining doubt, a forensic expert on maggots – such people do exist – testified that the theory of "semen-destroying maggots" was balderdash.
  • (5) Special care in the management of so-called 'chronic Lyme disease' is crucial lest the clinician prescribes prolonged or unending courses of antibiotics for such noninfectious problems.
  • (6) "The story is an extrapolation of what Mary Shelley did" explains writer Kevin Grevioux, lest there be any doubt.
  • (7) Loop sigmoid colostomy employing a stapling device and catheter irrigation of the distal segment is less time-consuming and has lest potential for contamination than the standard double-barrel colostomy.
  • (8) "Lest any holier-than-thou activists and politicians from other parties should forget, this is not just a Lib Dem issue, it is one that confronts women in all parties and in all professions.
  • (9) Whistleblowers with dual citizenship who speak out on Australia’s national security – including those involved in allegations that Timor-Leste’s cabinet room was bugged – could face having their citizenship revoked under proposed laws.
  • (10) You might have read a couple of articles in fashion magazines of late attempting to big up the DD look, no doubt with references to denim's "timelessness", "1950s teenage sense of freedom" and, lest we forget, "Americana".
  • (11) His film, The Angels' Share, a larky whisky heist, was screened with English as well as French subtitles at the festival, lest the Glaswegian accents prove a barrier for non-Scots.
  • (12) Article 6 of the EU treaty could not be clearer: “The union is founded on the principles of liberty, democracy, respect for human rights and fundamental freedoms, and the rule of law, principles which are common to the member states.” Lest this be regarded as mere rhetoric, Lord Bingham, the former senior law lord and widely regarded as the most outstanding British judge in the late 20th century, wrote in his book The Rule of Law (p67): “The European Commission has consistently treated democratisation, the rule of law, respect for human rights and good governance as inseparably linked.” This is why, today, we can work anywhere in the EU, have health cover throughout, bring back as much booze in the back of the van as we like, travel on cheap EU-based airlines (with the right to claim compensation for any delay), buy the villa in Marbella, and say what we like – and we can do all of these things with our rights fully protected by the law, just as if we were in the UK.
  • (13) Dahl’s heroine, Sophie, is a lonely young girl plucked from her bed in an orphanage by the titular behemoth, and carried off to Giant Land, his home, lest she alert the normal world to the presence of giants.
  • (14) A spokeswoman for the AFP did not confirm the particular section of the referral, but said in a statement: “On 13 December 2013, the Australian federal police received a referral from the Australian Security Intelligence Organisation relating to an allegation a former Australian intelligence officer disclosed information relating to operational activity in Timor-Leste.
  • (15) However, the author points out that these demonstration projects should be evaluated lest they continue to operate on the basis of rhetoric rather than fact.
  • (16) Since the clinical identification of these autoantigens often relies exclusively on size determination by Western blotting, we have characterized the commonly occurring fragments of histidyl-tRNA synthetase lest they confuse such identification.
  • (17) Lest we forget, Maradona only really got going in the quarter-finals.
  • (18) So, lest we are to be ruled solely by sociopaths and Blair's robot children, we should give them all a Bunbury option: a "Michael Green", under whose name to exercise all the human complexity for which modern politics cannot currently find room.
  • (19) Australia has made fresh promises limiting how it might use documents at the heart of a dispute with Timor-Leste , attempting to weaken the case for the international court of justice to order the sensitive material be surrendered.
  • (20) Lest there have been any remaining doubt, Donald Trump has confirmed a bully now resides in the White House.

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