(1) Here, we report the isolation and characterization of the beta-etherase gene, which contains an open reading frame of 843 bp and which we call ligE.
(2) Inherited as an autosomal recessive trait the syndrome is characterized by a medium degree generalized osteosclerosis, open craniial sutures and fontanels until adult lige, hypoplastic mandibles with deficiency of the angle, prominence of the forehead and occiput, hypoplasia of the paranasal sinuses, commonly observed dysproportionate dwarfism, acro-osteolysis and increased bone fragility.
(3) The long tissue half-lige of actinomycin D suggeststhat an intermittenr schedule of administration would be the most effective.
(4) In another reported incident, two men shoved an 18-year-old woman wearing a hooded sweatshirt, commented on religion and asked her: “Do you know you’re in America?” In the traditionally liberal city of Ann Arbor, two alleged incidents of ethnic intimidation and religious bias in a week is unusual, said Detective Lt Matthew Lige of the Ann Arbor police department.