(1) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(2) The sensitivity of 75 non-CNS solid tumors to mismatched dsRNA was compared to the high-grade astrocytomas in the HTCA.
(3) The mismatch was incorporated into the sequence d[CGG(AP)GGC].d-(GCCACCG).
(4) One enzyme (called all-type) can nick all eight base mismatches with different efficiencies.
(5) One-year graft survival was 98% in HLA-identical grafts (n = 73), 91% in haploidentical grafts (n = 411), 89% in 2 haplotype-mismatched related grafts (n = 38), and 85% in spousal donor grafts (n = 71).
(6) Jake Schmidt, international climate policy director at the green campaigning group Natural Resources Defence Capital, said: "There's a cultural mismatch between the Qatari team and this process.
(7) Each individual hairpin forms with mismatched base pairs, one containing two GT pairs and the other containing two AC pairs.
(8) In a severe renal failure case due to obstruction, the Authors have found a great mismatch in the results between the traditional methods and the radioisotopic ones.
(9) Op72a matches the consensus sequence, whereas Op72b contains two mismatches.
(10) The relative immaturity of the lymphoid system at birth may be advantageous in decreasing the graft versus host reaction if these cells are used in a mismatched transplantation.
(11) The unusual activity of IM effector preparations against HLA-mismatched LCLs arises from fortuitous cross-recognition of allogeneic cells by immunologically specific cytotoxic T cell clones coincidentally expanded in vivo alongside the EBV-specific response.
(12) The 3 groups were comparable with respect to recipient age, duration of dialysis, prior transfusions, previous transplants, cold ischemia time, HLA AB mismatches, cytotoxic antibody profile, posttransplant ATN, and prophylactic ALG treatment.
(13) Cleavage at a total of 13 T and 21 C mismatches isolated (by at least three properly paired bases on both sides) single-base-pair mismatches was identified.
(14) It seems likely that this novel activity is involved in a broad specificity DNA repair pathway for the correction of single base mismatches in human cells.
(15) These results suggested that depressed LV function in the patients with longstanding AS was largely related to limited preload reserve due to LV enlargement and mechanical unloading of LV (correction of afterload mismatch) resulted in improvement of LV function.
(16) The above results indicate that Y-body analysis is a simple and useful tool for the demonstration of bone marrow take in sex-mismatched BMT.
(17) This finding also suggests that the Hex, Mut, and PMS systems evolved from a common ancestor and that functionally similar mismatch repair systems could be widespread among procaryotic as well as eucaryotic organisms.
(18) In contrast to rapid rejection of MHC-mismatched heart allografts, differences at non-MHC histocompatibility antigens were associated with graft survival beyond 100 days, although chronic rejection of variable severity was detected histologically.
(19) Recipients of cadaver donor transplants which were not mismatched at HLA-A,B antigens had a 10% higher graft survival rate at one year than recipients of kidneys which were completely mismatched at HLA-A,B.
(20) The transfusion effect was greater in black (8%) than white (4%) recipients; however, the 77% 1-year graft survival rate for transfused black recipients of 0 DR-mismatched kidneys did not differ from that of transfused whites.
Uneven
Definition:
(a.) Not even; not level; not uniform; rough; as, an uneven road or way; uneven ground.
(a.) Not equal; not of equal length.
(a.) Not divisible by two without a remainder; odd; -- said of numbers; as, 3, 7, and 11 are uneven numbers.
Example Sentences:
(1) The local guide led us down a rough, uneven pathway, talking as he went.
(2) Using EIOM the determination of the homogeneous and uneven components of respiratory resistance was possible in control animals, whereas in AAE group resistance was entirely represented by its uneven component.
(3) While there has been some unevenness in the extent to which successful risk reeducation has occurred, it is nonetheless dramatic compared with prior health educational efforts, and especially so given the exceptional sensitivity of the sexual and illicit drug using behaviors at issue.
(4) "Of course this recovery which is starting is likely to be choppy and uneven.
(5) However, the number of abortion providers declined by five percent between 1982 and 1985, and the geographic distribution of abortion services continued to be markedly uneven.
(6) Tillerson described US progress on sanctions alongside China as uneven.
(7) The redistribution of the elderly population in the United States is receiving increased attention as the sociodemographic consequences of the uneven geography of the aged are becoming more evident to state and local policymakers.
(8) In most of the cases of MML there were unevenly distributed poorly defined leukemic, infiltrates in the renal cortex and medulla.
(9) Macroscopic and microscopic examination of plaster models obtained from impressions with alginate mass Kromopan Super and silicone mass Dentaflex Pasta confirmed that leaving of saliva and blood on the surface of impressions causes uneven surface of plaster models.
(10) A wide but uneven distribution was substantiated for the rat brain.
(11) The uneven geographic distribution of physicians has been identified as a significant problem for the delivery of health care services.
(12) What Katrina left behind: New Orleans' uneven recovery and unending divisions Read more Ten years on, resentment still lingers about the failure of the federal levee system during hurricane Katrina, the botched response of the Federal Emergency Management Agency (Fema), and the long and difficult process of accessing billions of dollars in grant money for rebuilding, which for some people is not finished.
(13) The computerized tomographic scans showed uneven wear of the glenoid surface, osteophytes, large cysts, and posterior displacement of the humeral head.
(14) The regional CMP distributions in the brains were uneven on both the 2nd and 7th experimental days.
(15) They are uneven ventilation throughout the lung; redistribution of regional pulmonary blood flow between zones due to gravity; nonuniform pulmonary blood flow between individual metarteriolar-capillary networks because of local vasoconstriction; uneven systemic blood flow between organs; irregular systemic blood flow at the microcirculatory level, producing inadequate nutritional flow to the tissues; and redistribution of body water, leading particularly to fluid accumulation in the extracellular compartment, with expanded interstitial space and contracted plasma volume (hypovolemia).
(16) Jeegar Kakkad at EEF, the manufacturers' organisation When viewed in the context of previous, often uneven recoveries, UK economic growth remains healthy with manufacturing enjoying the best 12 months since 1994.
(17) The hypotonic treatment was shown to result in differential decondensation of chromosomes which consists in the uneven distribution of deoxyribonucleoprotein (DNP) fibrils along chromatids.
(18) Mortality statistics were used to check the previously observed uneven geographical distribution of multiple sclerosis (MS) in Finland, and also to compare the distribution of tuberculosis and MS with each other.
(19) Additional impairments occur in a large percentage of patients, but are unevenly distributed in the disease groups.
(20) The uneven distribution of long term mentally ill patients suggests that community pyschiatric resources might be better targeted at those practices with higher numbers of such patients.