(n.) A line of ancestors; descent; lineage; genealogy; a register or record of a line of ancestors.
(n.) A record of the lineage or strain of an animal, as of a horse.
Example Sentences:
(1) Pedigree studies have suggested that there may be an inherited predisposition to many apparently nonfamilial colorectal cancers and a genetic model of tumorigenesis in common colorectal cancer has been proposed that includes the activation of dominantly acting oncogenes and the inactivation of growth suppressor genes.
(2) Several pedigrees have been reported in which defects of the insulin gene result in glucose intolerance or diabetes in affected members, but the role of insulin gene mutations in NIDDM is unknown.
(3) Another feature of TWINAN90 is the optional output of a pedigree file which can be read by the quantitative genetics package FISHER.
(4) ESD in conjunction with RB polymorphism would be useful in prenatal and presymptomatic diagnosis, as well as in carrier detection in informative pedigrees.
(5) This paper presents a FORTRAN IV subroutine to calculate inbreeding and kinship coefficients from pedigree information in a diploid population without self-fertilization.
(6) Histologic examination of one patient from each pedigree showed two characteristic findings in corneal epithelium; the previously designated "peculiar substance" in the cells, and the vacuolated homogeneous substance mostly within the cysts.
(7) While Elop has critics who say he did not fix Nokia or much of anything else in his long career in tech, others are likely to point to a pedigree that would also make him the favorite here.
(8) The pedigree analysis provided evidence of both a genetic effect (P less than 0.005) and an effect of increased dietary iron (P less than 0.005) on transferrin saturation and unsaturated iron-binding capacity.
(9) On the other hand, Sillence OI type I segregated with both COL1A1 (17 pedigrees) and COL1A2 (7 pedigrees).
(10) Using 166 pedigrees, reported in nine series available in the literature (including our own), we conclude that balanced insertion cannot entirely explain the familial data, even if we allow for a reduced viability of unbalanced gametes.
(11) To study the genetic influence on serum cholesterol levels and early coronary heart disease, 1,134 individuals were screened from 18 Utah pedigrees.
(12) An informative Dutch pedigree showed that two other linked polymorphic DNA markers, Pi227 and YN5.48, closely flank the FAP locus, one on either side.
(13) Discordant segregation between COL2A1 and the mutant locus was seen in pedigrees with multiple epiphyseal dysplasia, autosomal recessive spondyloepiphyseal dysplasia tarda, hypochondroplasia, pseudoachondroplasia, diaphyseal aclasis, and trichorhinophalangeal syndrome.
(14) Samples originated from eight schizophrenics and 27 relatives belonging to a large pedigree, thus ensuring biological homogeneity.
(15) We describe a codon 299 mutation in the glucokinase gene in a British pedigree with maturity-onset diabetes of the young (MODY) resulting in a substitution of glycine to arginine.
(16) We have studied five Italian pedigrees segregating schizophrenia using a map of four markers for the chromosomal region 5q11.2-13.3.
(17) Using three markers of chromosome 5, we have studied 28 additional French pedigrees.
(18) The phenotypically and often cytogenetically normal transmitting males in fragile X pedigrees are interpreted not as "nonpenetrant" transmitters of a fully formed fragile X but rather as transmitters of some or all of the factors necessary for TE insertion at Xq27.
(19) The problem has acquired practical importance because of the current international collaboration aimed at constructing a complete human linkage map of DNA markers through the study of three-generation pedigrees.
(20) Linkage analysis with four CMT1A pedigrees mapped the CMT1A gene with respect to two flanking markers (8B10-5 cM[LOD 5.2]-CMT1A-3.5 cM[LOD 5.3]-10E4).
Prestige
Definition:
(v.) Delusion; illusion; trick.
(v.) Weight or influence derived from past success; expectation of future achievements founded on those already accomplished; force or charm derived from acknowledged character or reputation.
Example Sentences:
(1) We carried English prestige into the inaugural season of the Europa League, taking Atlético Madrid into extra time in the final and within five minutes of a penalty shootout.
(2) Some offer a range, depending on whether you think you're a bit of a buff, and know a pinot meunier from a pinot noir and what prestige cuvée actually means or you just want to see a bit of the process and have a nice glass of bubbly at the end of it, before moving on to the next place – touring a pretty corner of France getting slowly, and delightfully, fizzled.
(3) We must abandon the opinion that the prestige of a surgical department rests in the number of beds.
(4) The researcher is completing a PhD on the superyacht scene and says the vessels are unique among prestige assets: unlike private jets they are not a useful mode of transport; unlike art and property, they always depreciate in value.
(5) It also said: “We should aim to break the right quickly, and teach those around us not to be intimidated by the rightwing’s longer years of service and apparently superior ‘Labour knowledge’ or prestige.” The July issue of the group’s newspaper, Solidarity, led with the headline “ Flood into the Labour party”.
(6) There are so many coaches in this world who want to work but can’t and there are those dashing blades who, through their quality and prestige, could work but don’t want to, because life as a parasite fulfils them professionally and economically.
(7) In London, for example, BP wants the prestige of being associated with the UK’s leading arts organisations.
(8) A study among a sample of Israeli primary care physicians and a comparison group of hospital physicians revealed an empirical 'structure of committedness', ascertaining that the committedness to practice primary care is contingent on the 'intrinsic' satisfaction and rewards as well as the 'extrinsic' rewards from the professional community (namely, prestige), derived from bio-medical (but not psycho-social) intervention activities.
(9) Two hundred ten adolescents were questioned regarding reasons they date, and the importance of various personality variables and prestige factors in selecting a dating partner.
(10) As deduced from Blau's theory, groups with greater relative occupational dispersion, greater political participation, advanced education, and higher sex ratios have greater relative occupational prestige in the health care delivery system.
(11) Over the years the Oscars have been variously coveted and sneered at, have increasingly brought box-office value and personal prestige, become a media obsession, a gauge of industrial morale and a way of taking the national pulse.
(12) "The military has suffered a huge blow to its prestige," said Cyril Almeida of Dawn newspaper.
(13) A factor analysis of the inventory revealed that students chose occupational therapy as a career because they liked the salaries, nationwide job availability, regular hours, and prestige that is associated with the profession.
(14) In The Prestige (2006), Christopher Nolan’s film about two battling magicians, Bowie featured as the inventor Nikola Tesla.
(15) Gaddafi, as vigilant keeper of the flame, kept a weather eye open, heaping privileges on some and prestige on others in order to consolidate alliances and plaster over any cracks that threatened to appear.
(16) The hunger strike by our former fellow prisoners at the Guantánamo prison camp should have already been the spur for President Obama to end this shameful saga, which has so lowered US prestige in the world.
(17) Olympic medals, Nobel prizes, the colour of coffee romances, prestige credit cards and superior chocolate from Terry's to Wispa .
(18) Other incentives to avoid misconduct may include a desire to earn re-election, the need to maintain prestige as an element of Presidential influence, and a President’s traditional concern for his historical stature.” Those checks and balances are likely to be tested when the business mogul-turned-president takes office.
(19) "Why are you ruining the prestige of the [UN nuclear] agency for absurd US claims?"
(20) Prestige, centre stage at the summit, the one-on-one meeting, the hand on the back from Trump.