(n.) A soldier detailed or employed to form roads, dig trenches, and make bridges, as an army advances.
(n.) One who goes before, as into the wilderness, preparing the way for others to follow; as, pioneers of civilization; pioneers of reform.
(v. t. & i.) To go before, and prepare or open a way for; to act as pioneer.
Example Sentences:
(1) It is the combination of his company's pan-African and industrialist vision – reminiscent of the aspirations of African independence pioneers like Ghana's Kwame Nkrumah – and its relentless financial growth that has set Dangote apart.
(2) Pioneers (41% of Britons) are global, networked, like innovation and believe in the importance of ethics.
(3) That's right, centuries of political columnists owe their careers to the pioneering efforts of Davy, Davy Crockett, the king of the wild frontier.
(4) Deputy Commissioner Catherine Burn ran the counter-terrorism operation under Task Force Pioneer, which was led by assistant commissioner Mark Murdoch, who reports to Burn.
(5) In this article the results of studies on the relationship between anaphylaxis and CNS, performed by both pioneers and contemporary investigators, are briefly reviewed.
(6) For example, where 2 longitudinal tracts are pioneered independently in grasshopper, only one is formed in Drosophila.
(7) At a time when the intrauterine diagnosis of hydrocephalus is commonplace and pioneering efforts of antenatal therapy are evolving, review of the chronology of treatment of this disorder becomes pertinent.
(8) Since acetylcholine (ACh) was identified as a neurotransmitter at parasympathetic nerve terminals by pioneering pharmacologists such as O. Schmiedeberg, R. Hunt, O. Loewi and H.H.
(9) The road to gaining nearly 1.2 billion monthly active users has seen the mums, dads, aunts and uncles of the generation who pioneered Facebook join it too, spamming their walls with inspirational quotes and images of cute animals, and (shock, horror) commenting on their kids' photos.
(10) But Olney wanted to be an artist and he set off for Paris, where he found himself a garret in which he could make portraits and a new life among friends, lovers and acquaintances that included the black American writer and civil rights pioneer James Baldwin, WH Auden and, distantly, Edith Piaf, whom he saw sing Je ne Regrette Rien for the first time at the Olympia theatre.
(11) He was a pioneer sexologist, demographer, and sportsman and an early Zionist.
(12) Their pioneering studies led to the continuing discoveries of antinuclear antibodies (ANA) and today's considerable knowledge concerning the molecular identity of antigens and further consolidation of ANA.
(13) The move signals a change for Democrats , who have traditionally shied away from gun control in a state with a pioneer tradition of gun ownership.
(14) Seven health habits, commonly referred to as the "Alameda 7," were shown to be associated with physical health status and mortality in a pioneer longitudinal study initiated in 1965 in Alameda County, CA.
(15) In a speech to the United Nations , Hu will declare that China is ready to pioneer a new low-carbon path of development, make a commitment to increase forest cover and pledge financial support for poorer nations to adapt to global warming, according to a source close to his delegation.
(16) Their growth cones pioneer a stereotyped pathway through the limb which becomes the route of one of the major leg nerve trunks.
(17) Just as the National Institute for Care and Health Excellence was the global pioneer for assessing new drugs and treatments in the last decade, London should become the pioneer for digital health technology assessments in the decade ahead.
(18) We, in the infection control field, are quality pioneers in hospitals.
(19) It is widely accepted that Sir James Young Simpson discovered the anaesthetic properties of chloroform and pioneered its application in surgery and midwifery.
(20) From its earliest days, Facebook has navigated – even pioneered – the territory around privacy, and how we express our personal identities online.
Trigger
Definition:
(n.) A catch to hold the wheel of a carriage on a declivity.
(n.) A piece, as a lever, which is connected with a catch or detent as a means of releasing it; especially (Firearms), the part of a lock which is moved by the finger to release the cock and discharge the piece.
Example Sentences:
(1) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(2) PMNs could be primed for PMA-triggered oxidative burst by muramyl peptide molecules (MDP) and two of its adjuvant active nonpyrogenic derivatives.
(3) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
(4) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
(5) Tactile stimulation of a coin-sized area in a T-2 dermatome consistently triggered a lancinating pain in the ipsilateral C-8 dermatome in a 38-year-old woman.
(6) It did the job of triggering growth, but it also fueled real-estate speculation, similar to what was going on in the mid-2000s here.” Slowing economic growth may be another concern.
(7) The findings suggest that mast cell prostaglandins are an important factor in the pathogenesis of pruritus and that local vascular responses may trigger mast cell degranulation.
(8) Among the agents triggering such an infection Chlamydia (30.9% of the cases of non-gonorrhoic urethritis), as well as mycoplasma, ureaplasma, anaerobic bacteria and herpes simplex viruses have gained particular significance.
(9) The role of surgery in triggering the reactivation of latent HSV-1, and the differences in rates of viral shedding between American and Japanese are discussed.
(10) The present results suggest that TMB-8 blocks twitches by preventing the release of Ca++ ions bound to the intracellular surface of the t-tubular membrane which is often called the store of 'trigger-calcium' ions.
(11) The figures, published in the company’s annual report , triggered immediate anger from fuel poverty campaigners who noted that energy suppliers had just been rapped over the knuckles by the Competition and Markets Authority (CMA) for overcharging .
(12) This is triggered not so much by climate change but the cause of global warming itself: the burning of fossil fuels both inside and outside the home, says Farrar.
(13) Although the Ca2+-independent mechanism accounts for about two thirds of the total acetylcholine release in the dark, the amount of acetylcholine released in this way is small compared with the release of acetylcholine triggered by stimulation of the retina with light.
(14) The results suggest an essential role of IL-6 for triggering of CD4+ T cells via the CD2 molecule.
(15) Defects in self-tolerance mechanisms could provide the genetic basis of disease or the target for environmental triggers.
(16) It is therefore suggested that salt water adaptation triggers a cellular reorganization of the epithelium in such a way that leaky junctions (a low resistance pathway) appear at the apex of the chloride cells.
(17) We report that kainic acid lesions of the posterior corpus striatum, which preferentially spare fibers of passage while destroying striatopallidal neurons, produce a stimulus-sensitive movement pattern in rats that has a highly specific sensory trigger.
(18) These results are consistent with the idea that RPE pigment dispersion is triggered by a substance that diffuses from the retina at light onset.
(19) The additional value of these methods, especially of the intensive monitoring, lies also in the possibility of compiling new knowledge about semiology and electro-clinical correlation of epileptic seizures, possible trigger mechanisms and long-term therapeutic effects.
(20) The publicity surrounding the Rotherham child exploitation scandal, which triggered the resignation of Shaun Wright, the previous PCC, did not translate into a high turnout, with only 14.65% of the electorate casting a vote.