(a.) Producing great physical effects; forcible; powerful' efficacious; as, a potent medicine.
(a.) Having great authority, control, or dominion; puissant; mighty; influential; as, a potent prince.
(a.) Powerful, in an intellectual or moral sense; having great influence; as, potent interest; a potent argument.
(n.) A prince; a potentate.
(n.) A staff or crutch.
(n.) One of the furs; a surface composed of patches which are supposed to represent crutch heads; they are always alternately argent and azure, unless otherwise specially mentioned.
Example Sentences:
(1) Neuromedin B (C50 6 x 10(-12) M) was 3 times less potent than bombesin-14.
(2) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells.
(3) administration of the potent short-acting opioid, fentanyl, elicited inhibition of rhythmic spontaneous reflex increases in vesical pressure (VP) evoked by urinary bladder distension.
(4) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(5) PBOP was as effective as polymyxin B nonapeptide (PMBN), the known very potent permeabilizer.
(6) )-induced gnawing behavior in rats was slightly more potent than that of clocapramine.
(7) We have confirmed this directly by showing that pure CCK is a potent inhibitor of gastric emptying.
(8) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(9) We conclude that human hepatic lipocytes synthesize TIMP-1, a potent metalloproteinase inhibitor, and that TIMP-1 expression increases with lipocyte activation.
(10) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
(11) Substance P, a potent vasodilating peptide, seems to be released from trigeminal nerve endings in response to nervous stimulation and is involved in the transmission of painful stimuli within the periphery.
(12) Addition in the cultures of 4-deoxypyridoxine, a potent antagonist of vitamin B6 coenzymes, concurrently with the mitogen, inhibits the induction of serine hydroxymethyltransferase.
(13) These findings suggest that Sch 40120 is a potent anti-inflammatory agent that may be particularly useful in the treatment of inflammatory diseases such as psoriasis in which leukotrienes appear to be major mediators of the pathological symptoms that characterize the disease state.
(14) Mercury compounds and EDTA were found to be potent inhibitors of proteinase yscJ activity.
(15) We found that whereas idarubicin was 2-5 times more potent than the other three anthracycline analogs against these tumor cell lines, idarubicinol was 16-122 times more active than the other alcohol metabolites against the same three cell lines.
(16) Concanavalin A (con A) is a potent inhibitor of coagulant activity of native tissue factor.
(17) The alpha 2-adrenoceptor agonist clonidine is most potent for stimulating Isc.
(18) Chlorpromazine was clearly the most potent antagonist in all three experimental conditions.
(19) Moreover, the ribosylation inhibitors converted the glucocorticoid antagonist RU-486 into a potent agonist for cytolysis of L1210 cells.
(20) Aortic rings from the rabbit were similarly potently antagonized by the protein kinase C inhibitors, however, K(+)-induced contractions were also equally sensitive to these agents in both rat and rabbit tissues.
Stiff
Definition:
(superl.) Not easily bent; not flexible or pliant; not limber or flaccid; rigid; firm; as, stiff wood, paper, joints.
(superl.) Not liquid or fluid; thick and tenacious; inspissated; neither soft nor hard; as, the paste is stiff.
(superl.) Firm; strong; violent; difficult to oppose; as, a stiff gale or breeze.
(superl.) Not easily subdued; unyielding; stubborn; obstinate; pertinacious; as, a stiff adversary.
(superl.) Not natural and easy; formal; constrained; affected; starched; as, stiff behavior; a stiff style.
(superl.) Harsh; disagreeable; severe; hard to bear.
(superl.) Bearing a press of canvas without careening much; as, a stiff vessel; -- opposed to crank.
(superl.) Very large, strong, or costly; powerful; as, a stiff charge; a stiff price.
Example Sentences:
(1) If you turn the bowl upside down, the whites should be stiff enough not to fall out.
(2) The stiffness of the fibre first rose abruptly in response to stretch and then started to decrease linearly while the stretch went on; after the completion of stretch the stiffness decreased towards a steady value which was equal to that during the isometric tetanus at the same sarcomere length, indicating that the enhancement of isometric force is associated with decreased stiffness.
(3) Current methodology for the in vitro determination of aortic and large artery stiffness is reviewed and involves three approaches: (1) the estimation of distensibility by pulse wave velocity measurement; (2) the estimation of distensibility from the fractional diameter change of a given arterial segment by imaging techniques (e.g., angiography, Doppler ultrasound) against pressure change; (3) the estimation of compliance by determining volume change against pressure change in the arterial system during diastolic runoff from the Windkessel model of the circulation.
(4) The maintenance of adequate blood circulation requires a sufficient ventricular contractility; in addition, to eject blood, the ventricles must first receive a sufficient volume, requiring a low diastolic stiffness.
(5) Stiffness was reduced in approximate proportion to the ramp stretch rate, and the reduction was confined largely to the elastic component.
(6) Proof stress, ultimate tensile strength, elongation, and plastic stiffness have been measured and results compared by use of analyses of variance.
(7) In other words, the stiffness of these areas was low and the recovery from deformation was fast.
(8) But the same court also just refused to hear an appeal of a Minnesota woman who's been ordered to pay more than $220,000 for downloading two-dozen songs – a testament to Congress' gift to Hollywood and its allies in the form of absurdly stiff penalties for minor infringement.
(9) The tension-length relation for the unstimulated (passive) cell is also linear between 1r and the elastic limit, but is displaced from the active tension-length curve and is of reduced stiffness.
(10) Bilaterals in summit seasons can be stiff exchanges, where digressions can carry risks: not enough said, too much said.
(11) We measured the stiffness of comparable configurations (1 or 2 bars) under axial compression, four-point-bending in two planes, and torsion.
(12) Tiny, tiny... rodents – some soft and grey, some brown with black stripes, in paintings, posters, wallcharts, thumb-tacked magazine clippings and poorly executed crayon drawings, hurling themselves fatally in their thousands over the cliff of their island home; or crudely taxidermied and mounted, eyes glazed and little paws frozen stiff – on every available surface.
(13) The bone stiffness also correlates strongly with the geometry (area) and slightly with bone mass; however, an unexpectedly low correlation was found between stiffness and density.
(14) Finally, fibrosis may paradoxically reduce passive stiffness if it leads to a thinning of the interventricular septum.
(15) A young male nephrotic patient, who was given small doses of clofibrate for hyperlipaemia, developed muscle pain, stiffness and very high serum levels of muscle enzymes.
(16) Impaired left ventricular stiffness may be an additional criterion for using corinfar in patients with coronary heart disease.
(17) The increase of elastic fibres following denervation and reinnervation represents an obviously meaningful reaction that may compensate for loss of tonic properties of muscle spindles without causing stiffness.
(18) Only the bone-patellar tendon-bone unit had maximum force and stiffness greater than that of the ACL.
(19) The initial stiffness is poorly described by material or catheter gauge.
(20) The stiffness tester and torque meter were found to yield nearly the same measurements of bending deformation for orthodontic wires as small as .007 inch diameter, provided the different bending apparatus are calibrated to each other.