(v. t.) To scold or rail at; to rate; to tease; to torment; to banter.
(n.) A piece of cloth torn off; a tattered piece of cloth; a shred; a tatter; a fragment.
(n.) Hence, mean or tattered attire; worn-out dress.
(n.) A shabby, beggarly fellow; a ragamuffin.
(n.) A coarse kind of rock, somewhat cellular in texture.
(n.) A ragged edge.
(n.) A sail, or any piece of canvas.
(v. i.) To become tattered.
(v. t.) To break (ore) into lumps for sorting.
(v. t.) To cut or dress roughly, as a grindstone.
Example Sentences:
(1) Over the past 20 years the rag-and-bone trade has had a makeover.
(2) I usually use them as a rag with which to clean the toilet but I didn’t have anything else to wear today because I’m so fat.” While this exchange will sound baffling to outsiders, to Brits it actually sounds like this: “You like my dress?
(3) Confluent monolayers of capillary endothelial cells derived from Mongolian gerbil brain were irradiated with a single exposure of x-rays, and their radiosensitivity and sequential changes in morphology, staining intensity for factor VIII-related antigen (F VIII RAg), and capacity to produce prostacyclin (PGI2) were examined.
(4) Skeletal muscle mtDNA of three patients with mitochondrial encephalomyopathy, characterized clinically by myoclonic epilepsy and ragged-red fiber (MERRF) syndrome, has been sequenced to determine the underlying molecular defect(s).
(5) A distinctive pattern of subsarcolemmal mitochondrial aggregates, referred to as "ragged red fibers" in human mitochondrial myopathies, was observed in muscle biopsy samples from 1 dog.
(6) Endothelial cells of capillary vessels showed positive binding by UEA-1 lectin and the presence of factor VIII RAG.
(7) Four of the mutants had no effect on chylous ascites, but two mutants linked with ragged, and one unlinked, showed a complex situation involving enhancement, inhibition, epistacy and other interactions.
(8) There was a slight shortening in the thrombin time and a smaller increase in post-operative FVIII RAg and FVIII RCof levels in the HES group.
(9) There was no correlation between FVIII:RAg levels and radiation pneumonitis, radiation dose, volume of irradiated lung, tumor burden, or time-interval between exposure and sampling.
(10) In one of these, a probe designed specifically to detect deleted mtDNA identified abundant deleted mtDNA and its fusion transcript in RRF and lesser accumulations in non-ragged red cytochrome oxidase (COX) deficient fibres.
(11) Only in fragments of the biceps brachii muscle histological and histochemical investigations showed mitochondrial changes of the type of "ragged-red fibres".
(12) In situ hybridization to intact thymus and RNA blot analysis of isolated thymic subpopulations separated on the basis of T cell receptor (TCR) expression demonstrated that both TCR- and TCR+ cortical thymocytes express RAG-1 and RAG-2 messenger RNA's.
(13) Nuclear run-on assays showed that TPA completely repressed the transcription of RAG-1 within 30 min.
(14) A former Socialist party leader, he is a jovial, wise-cracking believer in consensus politics, who aides say never loses his rag and who so hates fights that he was once nicknamed "the marshmallow" within his own party, or "Flanby", after a wobbly caramel pudding.
(15) The Farage adviser said he looked back on many people within Ukip as “a bunch of rag-tag, unprofessional, embarrassing people who let Nigel down at every juncture.” He told the Guardian: “Someone needs to go in there with a big stick.
(16) Furthermore, we show that RAG can be expressed not only by CD3-TCR negative but also by CD3-TCRab or gd positive T-ALL cells.
(17) After fusion of HPRT- RAG cells with E. lutescens fibroblasts we demonstrated that the enzymes HPRT and G6PD are localized on the presumptive X chromosome.
(18) We analyzed the mitochondrial DNA of blood cells of 5 patients from a Chinese family with myoclonic epilepsy and ragged-red fiber disease.
(19) A small percentage of peripheral B cells also contained RAG-1 mRNA, raising the possibility that this protein may also be involved in immunoglobulin class switching.
(20) Exposure of isolated thymocytes to 12-O-tetra-decanoylphorbol 13-acetate (TPA)+ionomycin rapidly abolishes the expression of recombination-activating gene-1 (RAG-1) mRNA (3 h), down-regulates CD4 surface antigen expression (3 h), and enhances apoptosis (24 h).
Ras
Definition:
(n.) See 2d Reis.
Example Sentences:
(1) The effects of hormonal promotion of T24-ras oncogene-transfected rat embryo fibroblasts (REF) were compared to cotransformation of these cells with adenovirus E1A and ras.
(2) Large gender differences were found in the correlations between the RAS, CR, run frequency, and run duration with the personality, mood, and locus of control scores.
(3) Here we co-inject RB protein with c-myc, EJ-ras, c-fos or c-jun protein.
(4) These results suggest that a certain minimum level of expression of c-myc is required for the maintenance of ras transformation in NIH 3T3 cells.
(5) This is the first clear example of activation of the K-ras gene by ethylating agents in a rodent lung tumor system.
(6) A total of 28 cell lines were selected for Geneticin - resistance and inoculated into the footpads of syngeneic animals following co-transfection with pSV2neo and genomic DNA, or transfection with plasmid constructs containing neo and the activated Ha-ras oncogene.
(7) In the second study, CFA, TiterMax, Adjuvax and RAS were compared in rabbits, mice and goats.
(8) One week after initiation is 1-2 months before the appearance of benign papillomas that harbor activated Ha-ras oncogenes when the initiated mice are promoted with the tumor promoter phorbol 12-myristate 13-acetate.
(9) The other three oncogenes namely c-K-ras, c-H-ras and c-myc, were not detected in these two carcinomas or the non-cancerous liver tissue adjacent to the carcinomas.
(10) Thus, a4 and a2 alleles of the c-Ha-ras-1 may perhaps be viewed as genetic markers of predisposition to lung, ovarian and thyroid cancer, respectively, in combination with other clinical parameters.
(11) Additionally, the amount of mRNAs for preproenkephalin as well as for the cellular proto-oncogenes c-myc, c-fos and c-H-ras, which are thought to be mediators of intracellular signal transduction, was determined in hippocampus in these same animals.
(12) The degree of staining for ras 11 was significantly related to the grade of differentiation and increased from Dukes stage A to C. Strong staining for ras 11 predicted a significantly shorter recurrence-free interval (p less than 0.001).
(13) The effects of oxidant stress were studied in immortalised hamster (BHK-21) and rat (208F) cell lines before and after transformation to the malignant state with polyoma virus, or activated H-ras, respectively.
(14) Upon stimulation with NGF, the percentage of Ras.GTP increased to 24% after 2 min, and the high level of Ras.GTP was maintained for at least 16 h. On the other hand, the activation of Ras by FGF and IL-6 showed distinct kinetics; about 3-fold increase of Ras.GTP was detected at 10 min, and afterward, the level returned to the basal level within 60 min.
(15) Transfection with normal and activated C-H-ras oncogenes only led to increases in the IC50s of alkylating agents.
(16) These cell lines also overexpress the Ha-ras proto-oncogene.
(17) In one patient with gastric carcinoma a c-Ha-ras-1 overexpression was detected due to its amplification both in tumour tissues and in regional metastasis.
(18) Our study gives further evidence that erb B, myc, Ha-ras and fos proto-oncogenes are involved in the control of cell growth and in the process of rat hepatocarcinogenesis.
(19) The Wap-ras gene was stably introduced into the mouse germ line of five transgenic mice (one male and four females).
(20) These results suggest that ras, fos, mos, src, and erbB-2 use a common cellular pathway for transforming cells.