(n.) Concreted earthy or mineral matter; also, any particular mass of such matter; as, a house built of stone; the boy threw a stone; pebbles are rounded stones.
(n.) A precious stone; a gem.
(n.) Something made of stone. Specifically: -
(n.) The glass of a mirror; a mirror.
(n.) A monument to the dead; a gravestone.
(n.) A calculous concretion, especially one in the kidneys or bladder; the disease arising from a calculus.
(n.) One of the testes; a testicle.
(n.) The hard endocarp of drupes; as, the stone of a cherry or peach. See Illust. of Endocarp.
(n.) A weight which legally is fourteen pounds, but in practice varies with the article weighed.
(n.) Fig.: Symbol of hardness and insensibility; torpidness; insensibility; as, a heart of stone.
(n.) A stand or table with a smooth, flat top of stone, commonly marble, on which to arrange the pages of a book, newspaper, etc., before printing; -- called also imposing stone.
(n.) To pelt, beat, or kill with stones.
(n.) To make like stone; to harden.
(n.) To free from stones; also, to remove the seeds of; as, to stone a field; to stone cherries; to stone raisins.
(n.) To wall or face with stones; to line or fortify with stones; as, to stone a well; to stone a cellar.
(n.) To rub, scour, or sharpen with a stone.
Example Sentences:
(1) Among its signatories were Michael Moore, Oliver Stone, Noam Chomsky and Danny Glover.
(2) Follow-up studies using radiological methods show worse results (recurrent stones in II: 21.2%, in I: 5.8%, stenosis of EST in II: 6.1%, in I: 3.1%): Late results of EST because of papillary stenosis are still worse compared to those of choledocholithiasis.
(3) Other serious complications were reservoir perforation during catheterisation in 3 and development of stones in the reservoir in 2 patients.
(4) In conclusion, 1) etiology of urinary tract stone in all recurrent stone formers and in all patients with multiple stones must be pursued, and 2) all stones either removed or passed must be subjected to infrared spectrometry.
(5) Predisposition to pancreatitis relates to duct size rather than stone size per se.
(6) Three of these patients, who had a solitary stone could successfully be treated by ESWL as monotherapy.
(7) In cholesterol stones and cholesterolosis specimens, relatively strong muscle strips had similar responses to 10(-6) M cholecystokinin-8 in normal calcium (2.5 mM) and in the absence of extracellular calcium.
(8) No significant complications were related to ESWL and 90% of those followed up after successful ESWL proved stone-free at 6 weeks.
(9) The addition of alcohol to the drinking-water resulted in the formation of stones rich in pigment.
(10) One biliary stone showed cholesterol with spherical bodies of calcium carbonate and pigment.
(11) Israel has complained in recent weeks of an increase in stone throwing and molotov cocktail attacks on West Bank roads and in areas adjoining mainly Palestinian areas of Jerusalem, where an elderly motorist died after crashing his car during an alleged stoning attack.
(12) The first problem facing Calderdale is sheep-rustling Happy Valley – filmed around Hebden Bridge, with its beautiful stone houses straight off the pages of the Guardian’s Lets Move To – may be filled with rolling hills and verdant pastures, but the reality of rural issues are harsh.
(13) The minimal advantage in rapidity of stone dissolution offered by tham E over tham is more than offset by the considerably increased potential for toxic side effects.
(14) The Broken King by Philip Womack Photograph: Troika Books The Sword in the Stone begins with Wart on a "quest" to find a tutor.
(15) It is no longer necessary for the kidney to be free of stones at the end of the operation.
(16) So let's be clear: children taking this drug, which is administered orally, do not get stoned.
(17) Patients with unilateral renal stone(s) with at least 1 diameter between 7 and 25 mm.
(18) Whether they affect ureteral motility in vivo or whether they can counteract ureteral spasm associated with ureteral stones have not been established.
(19) Recurrent stones are usually "silent," and we do not usually treat asymptomatic stones.
(20) Forty impressions were poured with the disinfectant dental stone and a similar number were poured with a comparable, nondisinfectant stone.
Terminus
Definition:
(n.) Literally, a boundary; a border; a limit.
(n.) The Roman divinity who presided over boundaries, whose statue was properly a short pillar terminating in the bust of a man, woman, satyr, or the like, but often merely a post or stone stuck in the ground on a boundary line.
(n.) Hence, any post or stone marking a boundary; a term. See Term, 8.
(n.) Either end of a railroad line; also, the station house, or the town or city, at that place.
Example Sentences:
(1) Conditions for limited digestion of the heterodimer by subtilisin, removing only the carboxyl terminus, were determined.
(2) The elongation of helix III with the addition of helix II at the N-terminus somewhat stabilizes the ordered structure.
(3) Synthetic DNA corresponding to the hydrophobic domain of cytochrome b5 was enzymatically fused in-frame to cloned DNA corresponding to the C-terminus of the Escherichia coli enzyme, beta-galactosidase.
(4) TCR beta chain gene expression of individual T cell clones that share the same MHC class II restriction and similar fine specificity for the encephalitogenic NH2 terminus of the autoantigen myelin basic protein (MBP) has been examined.
(5) When these sequences were fused to the N terminus of yeast cytochrome oxidase subunit IV lacking its own presequence, they directed the attached subunit IV to its correct intramitochondrial location in vivo.
(6) Both proteins appeared to be recognized by antibodies against the amino (N) terminus of the alpha 1 subunit sequence.
(7) These plasmin-cleaved peptides are derived from the COOH terminus of C2b, and they induce the contraction of estrous rat uterus.
(8) From the decreased alignment at the N-terminus and the presence of additional residues compared with bacterial phosphorylases, we conclude that the regulatory sequences that also carry the phosphorylation site in the muscle enzyme were joined to a presumed ancestral precursor gene by gene fusion after separation of the eukaryotic and prokaryotic lines of descent.
(9) Microsequencing of the peptides resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicates that the amino terminus of the protein is disposed at or near the cytoplasmic surface of the gap junction, and that this surface also contains a protease-hypersensitive hydrophilic sequence between residues 109 and 123, presumably connecting the second and third transmembrane segments.
(10) The N-terminal sequence (15 amino acid residues) of the L-proline activating fragment obtained by trypsin treatment was identical with that of GS2, indicating that the L-proline activating site is located at the N-terminus of the native synthetase.
(11) It is suggested that a general manner of folding may be a common feature of the heterogeneous population of kappa-chains: one bridge which folds an invariable stretch of the chain, another bridge which folds a stretch that varies from protein to protein, and a bridge at the C-terminus which is the interchain link.
(12) Cysteine proteinase I cleaved peptides primarily from the C-terminal region of Tg, which contained two major hormonogenic sites, while cathepsin-B produced peptides mainly from the N-terminus, containing another major hormonogenic site.
(13) Deletions from the N terminus of LMM did not alter the solubility properties of the expressed material, but deletion of 92 residues from the C terminus caused a large increase in solubility at low ionic strength, indicating that a determinant important for interaction between LMM molecules was located in this region.
(14) Middle component particles of bean pod mottle virus (BPMV) containing small protein subunits with a cleaved C terminus were used to produce monoclonal antibodies (MAbs).
(15) We find that the NH2-terminus of PTH is rapidly degraded in situ by the liver but that both liver and especially kidney nevertheless contain low levels of NH2-terminal PTH fragments that, although not released into the blood, are large enough to be potentially active.
(16) 2) By contrast, the COOH terminus is an inhibitory regulator of mitogenesis, and removal of the terminal 43 amino acids converts the receptor from a moderately active growth signaler to a very active one.
(17) Since the HPV-16 E6-promoted degradation involves the ubiquitin-dependent proteolysis pathway, specific mutations were made in the amino terminus of p53 to examine whether the E6 targeted degradation involved the N-end rule pathway.
(18) Examination of the inhibitory effect of ATP using oligo(dA)12-18 as well as activated DNA as primers revealed that (a) ATP inhibition is not due to its addition onto a 3'-OH primer terminus ad judged by the lack of incorporation of labeled ATP, although under similar conditions incorporation of GTP can be demonstrated, (b) a consistent degree of inhibition was noted independent of primer or enzyme concentration; (c) addition of ATP to an ongoing reaction promptly reduces the rate of polymerization; (d) kinetic studies indicate a competitive (with respect to substrate deoxy triphosphate) pattern of inhibition; (e) addition of excess deoxyribotriphosphate promptly relieves the inhibition.
(19) A peptide corresponding to the COOH terminus (residues 45-65) was synthesized utilizing lysine 47 as a specific residue to conjugate to thyroglobulin as a carrier for raising antibodies in mice.
(20) Myristic acid-labeled virions contained a single radioactive protein, p10, supporting the mapping of this molecule to the amino terminus.