(n.) To unite or knit together confusedly; to interweave or interlock, as threads, so as to make it difficult to unravel the knot; to entangle; to ravel.
(n.) To involve; to insnare; to entrap; as, to be tangled in lies.
(v. i.) To be entangled or united confusedly; to get in a tangle.
(n.) Any large blackish seaweed, especially the Laminaria saccharina. See Kelp.
(v.) A knot of threads, or other thing, united confusedly, or so interwoven as not to be easily disengaged; a snarl; as, hair or yarn in tangles; a tangle of vines and briers. Used also figuratively.
(v.) An instrument consisting essentially of an iron bar to which are attached swabs, or bundles of frayed rope, or other similar substances, -- used to capture starfishes, sea urchins, and other similar creatures living at the bottom of the sea.
Example Sentences:
(1) The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy.
(2) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(3) Although a trend was observed for TMA-DPH mobility to parallel histopathologic severity in hippocampal specimens, the biophysical changes did not appear to reflect a loss of neuronal membranes relative to glial membranes or the presence of senile plaques or neurofibrillary tangles.
(4) Neurofibrillary tangles (NFT), one of the pathological hallmarks of Alzheimer's disease are observed in very high densities in the brains of former professional boxers suffering from dementia pugilistica.
(5) Elevated brain Al concentrations, especially in cortical regions, were associated with behavioral changes and the development of neurofibrillary tangles (NFTs).
(6) The smoky density of the mackerel was nicely offset by the pointed black olive tapenade and the fresh, zingy flavours present in little tangles of tomato, shallot, red pepper and spring onion, a layer of pea shoots and red chard, and the generous dressing of grassy olive oil.
(7) Changes were more severe in white matter close to cortical areas with a great density of neurofibrillary tangles.
(8) There is a tangled web between Salazar, Nike, Farah and the Nike Oregon Project on one hand, and the British Athletics performance director, Neil Black, and head of endurance, Barry Fudge, on the other.
(9) Whereas cortical senile plaque count did not distinguish well between demented and nondemented subjects, every subject with numerous cortical neurofibrillary tangles was demented.
(10) Clinical symptoms of amnesia appear when amyloid induces neighbouring neuritic alterations: paired helical filaments and distant neuronal body lesions: neurofibrillary tangles.
(11) Staggerer cerebellar cortex exhibits the greatest fluorescence with most terminals appearing as matted tangles adjacent cell bodies.
(12) Tangle-free neurons in both diseased and control brains showed weak to absent intracytoplasmic immunoreactivity.
(13) But tangled up in its visions of thousands of new “starter homes” – 5,000 more of which were promised on Monday, when the government said it was going to directly commission housebuilding on five sites in the south of England – are an array of drastic measures aimed at what remains of England’s council homes.
(14) The capacity for protein synthesis in tangled cells appears, therefore, to be progressively decreased with accumulation of tangle, whereas that for oxidative metabolism is maintained and lysosomal activity, perhaps, increased.
(15) On electron microscopy the normal lamellar pattern made up of orientated collagen fibrils all about 80 nm diameter is replaced by a random tangled pattern of much thinner irregularly curved fibrils, some as thin as 5nm.
(16) Eight brains failed to reveal considerable numbers of neuritic plaques, neurofibrillary tangles, and neuropil threads, but these brains showed the presence of abnormal and intensely argyrophilic grains loosely scattered throughout the neuropil.
(17) N-Terminal and C-terminal domains of tau were found to be present in tangles in situ.
(18) The neuropathological lesions were assessed using a fluorescent stain for neuritic plaques and neurofibrillary tangles.
(19) However, increased knowledge concerning macromolecular abnormalities in amyloid containing plaques and neurofibrillary tangles makes the outlook for a diagnostic test for AD on CSF promising.
(20) The trial, originally expected to be staid, has exposed severe dysfunction within Bo's family and detailed the complicated tangle of allegiances and affairs that led to his downfall .