(a.) Sour, sharp, or biting to the taste; tart; having the taste of vinegar: as, acid fruits or liquors. Also fig.: Sour-tempered.
(a.) Of or pertaining to an acid; as, acid reaction.
(n.) A sour substance.
(n.) One of a class of compounds, generally but not always distinguished by their sour taste, solubility in water, and reddening of vegetable blue or violet colors. They are also characterized by the power of destroying the distinctive properties of alkalies or bases, combining with them to form salts, at the same time losing their own peculiar properties. They all contain hydrogen, united with a more negative element or radical, either alone, or more generally with oxygen, and take their names from this negative element or radical. Those which contain no oxygen are sometimes called hydracids in distinction from the others which are called oxygen acids or oxacids.
Example Sentences:
(1) The amino acid sequence deduced from the nucleotide sequence contained both amino- and carboxyl-terminal sequences.
(2) F(420) is photolabile aerobically in neutral and basic solutions, whereas the acid-stable chromophore is not photolabile under these conditions.
(3) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
(4) If ascorbic acid was omitted from the culture medium, the extensive new connective tissue matrix was not produced.
(5) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
(6) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
(7) An unsaturated fatty acid auxotroph of Escherichia coli was grown with a series of cis-octadecenoate isomers in which the location of the double bond varied from positions 3 to 17.
(8) The ability of azelastine to influence antigen-induced contractile responses (Schultz-Dale phenomenon) in isolated tracheal segments of the guinea-pig was investigated and compared with selected antiallergic drugs and inhibitors of arachidonic acid metabolism.
(9) After 4 to 6 hours of recirculation, accumulation of vasoactive amine, 5-hydroxytryptamine, its major metabolite, 5-hydroxyindole acetic acid, and its precursor amino acid, tryptophan were detected.
(10) Spectrophotometric determination of the sulfhydryl content in the animal tissue before (control) and after using 6,6'-Dithiodinicotinic acid is applied.
(11) This death is also dependent on the presence of chloride and is prevented with the non-selective EAA antagonist, kynurenic acid, but is not prevented by QA.
(12) However, four of ten young adult outer arm (relatively sun-exposed) and one of ten young adult inner arm (relatively sun-protected) fibroblasts lines increased their saturation density in response to retinoic acid.
(13) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(14) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(15) Estimations of the degree of incorporation of 14C from the radioactive labeled carbohydrate into the glycerol and fatty acid moieties were carried out.
(16) The second amino acid residue influences not only the rate of reaction but also the extent of formation of the product of the Amadori rearrangement, the ketoamine.
(17) Leumorphin is a 29-amino-acid peptide derived from preproenkephalin B. Intracerebroventricular (i.c.v.)
(18) Hepatic lymph flow increased only after ethacrynic acid and mannitol administration.
(19) The subcellular distribution of sialyltransferase and its product of action, sialic acid, was investigated in the undifferentiated cells of the rat intestinal crypts and compared with the pattern observed in the differentiated cells present in the surface epithelium.
(20) A phytochemical investigation of an ethanolic extract of the whole plant of Echites hirsuta (Apocynaceae) resulted in the isolation and identification of the flavonoids naringenin, aromadendrin (dihydrokaempferol), and kaempferol; the coumarin fraxetin; the triterpene ursolic acid; and the sterol glycoside sitosteryl glucoside.
Dose
Definition:
(n.) The quantity of medicine given, or prescribed to be taken, at one time.
(n.) A sufficient quantity; a portion; as much as one can take, or as falls to one to receive.
(n.) Anything nauseous that one is obliged to take; a disagreeable portion thrust upon one.
(n.) To proportion properly (a medicine), with reference to the patient or the disease; to form into suitable doses.
(n.) To give doses to; to medicine or physic to; to give potions to, constantly and without need.
(n.) To give anything nauseous to.
Example Sentences:
(1) This trend appeared to reverse itself in the low dose animals after 3 hr, whereas in the high dose group, cardiac output continued to decline.
(2) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(3) Age difference did not affect the mean dose-effect response.
(4) The rash presented either as a pityriasis rosea-like picture which appeared about three to six months after the onset of treatment in patients taking low doses, or alternatively, as lichenoid plaques which appeared three to six months after commencement of medication in patients taking high doses.
(5) Neutrons induced a dose-dependent cytotoxicity and mutation frequency in the AL cells.
(6) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).
(7) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(8) The fraction of the viral dose which became cell associated was independent of the incubation temperature and increased with increasing target membrane concentration.
(9) The second group only with Haloperidol (same dose).
(10) The level of gadd45 mRNA increased rapidly after X rays at doses as low as 2 Gy.
(11) The cumulative incidence of grade II and III acute GVHD in the 'low dose' cyclosporin group was 42% compared to 51% in the 'standard dose' group (P = 0.60).
(12) The diffusion of Myocamicin in the prostatic tissue of patients undergoing prostatectomy after a single oral dose of 600 mg has been studied.
(13) In X-irradiated litters, almost invariably, the incidence of anophthalmia was higher in exencephalic than in nonexencephalic embryos and the ratio of these incidences (relative risk) decreased toward 1 with increasing dose.
(14) Similarly, doses of deferoxamine at the time of the study were not different.
(15) A survey carried out two and three years after the launch of the official campaign also showed a reduction in the prevalence of rickets in children taking low dose supplements equivalent to about 2.5 micrograms (100 IU) vitamin D daily.
(16) A quantitative comparison of tissue distribution and excretion of an orally administered sublethal dose of [3H]diacetoxyscirpenol (anguidine) was made in rats and mice 90 min, 24 hr, and 7 days after treatment.
(17) The inhibitory effects were stronger in A549 lung cancer cells than in HEL cells at the same TFP dose.
(18) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(19) Pituitary weight, mitotic index and chromosomes were studied in male rats following a single or repeated dose of estradiol-benzoate for a total period of 210 days.
(20) Estimates of the risk probability for each dose level and sacrifice time are found utilizing the sample likelihood as the posterior density.