(n.) The state of being deficient; inadequacy; want; failure; imperfection; shortcoming; defect.
Example Sentences:
(1) The goals of treatment are the restoration of normal gut peristalsis and the correction of nutritional deficiencies.
(2) These deficiencies in the data compromise HIV surveillance based on diagnostic testing, and supplementary bias-free data are needed.
(3) Congenitally deficient plasmas were used as the substrate for the measurement of procoagulant activities in a one-stage clotting assay.
(4) In contrast, idiopathic GH deficient girls have an onset of puberty and PHV nearer to a normal chronological age and at an early bone age.
(5) The ACTH deficiency recovered spontaneously, with normal cortisol responses to depot Synacthen (greater than 1380 at 6 h) and hypoglycemia (peak, 590) 14 and 18 months postpartum, respectively.
(6) One hundred and twelve dogs, including twenty C3-deficient dogs, were studied over a period of 6 years.
(7) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(8) Paired tolbutamide and glucose infusions using a square wave technique demonstrated that although early phase insulin secretion is dimished in the fetus, this is not due to an absolute deficiency of stored insulin.
(9) A significant association between G6PD deficiency and hemoglobin S correlated with previous studies on similar samples from the general population.
(10) We describe 10 patients with cerebral venous thrombosis: two had protein S deficiency, one had protein C deficiency, one was in early pregnancy, and there was a single case of each of the following: dural arteriovenous malformation, intracerebral arteriovenous malformation, bilateral glomus tumours, systemic lupus erythematosus, Wegener's granulomatosis, non-Hodgkin's lymphoma.
(11) A newborn presenting with persistent umbilical stump bleeding should be screened for factor XIII deficiency when routine coagulation tests prove normal.
(12) Recognition of this deficiency in our knowledge spurred a belated explosion of research that began with an exploration of the fine structure of the mesothelium.
(13) C. parasitica mutant strains deficient in the production of endothiapepsin (eapA-) were constructed using a gene-replacement strategy.
(14) Clinicians should be aware of this new and unusual association of a cerebral glioma and acquired immune deficiency syndrome.
(15) We have previously reported the isolation of a genomic clone encoding human liver-specific peroxisomal alanine:glyoxylate aminotransferase (AGT, EC 2.6.1.44), the deficient enzyme in primary hyperoxaluria type 1 (PH1) (P. E. Purdue, Y. Takada, and C. J. Danpure, J.
(16) Natural killer (NK) cell activity was assessed in the peripheral blood of 20 patients with growth hormone (GH) deficiency due to a hypothalamic deficit of GH-releasing hormone (GHRH).
(17) The results show that of 543 subjects with AA haemoglobin, 106 (19.5%) were G-6-PD deficient and of 93 individuals with AS haemoglobin 13 (14.0%).
(18) Basal plasma levels of oxytocin were found to be low in sodium-deficient adrenalectomized rats and in intact animals treated daily with desoxycorticosterone acetate, both of which groups drank large amounts of NaCl solution, whereas basal plasma levels of arginine vasopressin were neither stimulated nor suppressed.
(19) ACTH also suppressed aldosterone biosynthesis in rats kept on a sodium-deficient diet.
(20) The duodenal mucosa of genotypically normal iron replete and iron deficient mice and mice with sex-linked (sla) and microcytic anemias (mk) was examined for the presence of iron-binding proteins.
Lack
Definition:
(n.) Blame; cause of blame; fault; crime; offense.
(n.) Deficiency; want; need; destitution; failure; as, a lack of sufficient food.
(v. t.) To blame; to find fault with.
(v. t.) To be without or destitute of; to want; to need.
(v. i.) To be wanting; often, impersonally, with of, meaning, to be less than, short, not quite, etc.
(v. i.) To be in want.
(interj.) Exclamation of regret or surprise.
Example Sentences:
(1) Here we have asked whether protection from blood-borne antigens afforded by the blood-brain barrier is related to the lack of MHC expression.
(2) tRNA from mutant IB13 lacks 5-methylaminomethyl-2-thio-uridine in vivo due to a permanently nonfunctional methyltransferase.
(3) BL6 mouse melanoma cells lack detectable H-2Kb and had low levels of expression of H-2Db Ag.
(4) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(5) In the past, the interpretation of the medical findings was hampered by a lack of knowledge of normal anatomy and genital flora in the nonabused prepubertal child.
(6) A diplomatic source said the killing appeared particularly unusual because of Farooq lack of recent political activity: "He was lying low in the past two years.
(7) The present study examined whether the lack of chronic hemodynamic effects of ANP in control rats was due to changes in vascular reactivity to the peptide.
(8) Since it was established, it has stoked controversy about contemporary art, though in recent years it has been more notable for its lack of sensationalism.
(9) Inadequate treatment, caused by a lack of drugs and poorly trained medical attendants, is also a major problem.
(10) Because of the small number of patients reported in the world literature and lack of controlled studies, the treatment of small cell carcinoma of the larynx remains controversial; this retrospective analysis suggests that combination chemotherapy plus radiation offers the best chance for cure.
(11) I would immediately look askance at anyone who lacks the last and possesses the first.
(12) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(13) Core enzyme, lacking omega subunit, catalyzed this reaction at a rate less than 1% that of holoenzyme.
(14) But not only did it post a larger loss than expected, Amazon also projected 7% to 18% revenue growth over the busiest shopping period of the year, a far cry from the 20%-plus pace that had convinced investors to overlook its persistent lack of profit in the past.
(15) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(16) Thus the failure to raise anti-Id with internal image characteristics may provide an explanation for the lack of anti-gp120 activity reported in anti-Id antisera raised to multiple anti-CD4 antibodies.
(17) His walkout reportedly meant his fellow foreign affairs select committee members could not vote since they lacked a quorum.
(18) In South Africa, health risks associated with exposure to toxic waste sites need to be viewed in the context of current community health concerns, competing causes of disease and ill-health, and the relative lack of knowledge about environmental contamination and associated health effects.
(19) The functional capacity to present antigens to T cells was lacking in normal resting B cells, but was acquired following LK treatment.
(20) These findings indicate an association between HLA-B7 and ankylosing spondylitis in American blacks and suggest that these patients who lack B27 but possess B7 represent a subgroup of patients with this disease.