(a.) Inspiring dread; impressing great fear; fearful; terrible; as, a dreadful storm.
(a.) Inspiring awe or reverence; awful.
Example Sentences:
(1) Thinking I had the dreaded Norovirus, I rushed home.
(2) We should be grateful the School Food Trust has established this now, before we end up falling down a slippery slope back towards the dreaded Turkey Twizzler that Jamie Oliver campaigned to banish," he added.
(3) So what should those who have long dreaded this moment do now?
(4) Dr Bhambra sustained the most dreadful life-changing injuries during a sustained racist attack on an innocent man, a member of a caring profession.” There was applause from the public gallery as the verdict was returned.
(5) Despite a dreadful end to last season, culminating in a 6-1 defeat at Stoke City, FSG are pressing ahead with transfer plans agreed with Rodgers, indicating the manager’s position is safe at the moment.
(6) The image of older people, epitomised in the dreadful road sign, is about health and disability, but poverty is an equally defining feature, so we could talk about older people dependent on social security and those who have other sources of income.
(7) Panic attacks would overwhelm her periodically and she experienced regular “ scanxiety ” – the feelings of dread that grip patients before new tests.
(8) If you are a London commuter dreading tube strike chaos this evening and tomorrow there is an alternative to fighting your way on to overcrowded buses or a long walk.
(9) Many clinicians have realised that AIDS is only the most dreadful aspect of HIV infection.
(10) I have to say I think Iran are the poorest team I've seen so far – Nigeria were dreadful in that game but you got the sense that at leas they were a half-decent team playing badly.
(11) After expressing frustration with Stoke City's style of play, the dreadful standard of the game and the lack of width available on a pitch narrowed to exploit Rory Delap's throw-ins, Tony Mowbray finally realised that a sixth defeat in seven matches might also owe something to West Bromwich Albion's shortcomings.
(12) Thus China replaced a state bureaucracy with a similar state bureaucracy under a different name, the USSR replaced the dreaded imperial secret police with an even more dreaded secret police, and so forth.
(13) It's unfair to single him out on the basis of a performance in which almost all of his team-mates have been dreadful, but he's been consistently awful throughout this tournament and keeps getting picked.
(14) They'll dread the same thing happening again, possibly during an election campaign.
(15) Despite his humorous dismissal of the danger, those close to him dreaded the trips, with the archbishop of York, Dr John Sentamu, admitting: "My heart is in my mouth every time he goes to Nigeria."
(16) So Richard arose as himself again, a dreadful apparition cavorting.
(17) Try Penny Dreadful Read more Conleth Hill, who plays Machiavellian royal fixer Varys, kept the crowd in stitches.
(18) Even after yesterday's dreadful GDP figures , a year on from the financial firestorm, it has become apparent that we are not about to suffer a full rerun of America's Great Depression.
(19) CSKA Moscow survive PSV Eindhoven fightback after Seydou Doumbia double Read more Van Gaal, clearly unenthused by the team’s display, cannot have missed another limited performance from Wayne Rooney, most notable for a fairly dreadful shot when Anthony Martial’s quick feet and directness gave him a chance after 20 minutes.
(20) Soubry compared nicotine to heroin as she spoke of how she found it difficult to give up smoking because nicotine is a "dreadful substance" that creates a "perverse psychology of smoking".
Severe
Definition:
(superl.) Serious in feeeling or manner; sedate; grave; austere; not light, lively, or cheerful.
(superl.) Very strict in judgment, discipline, or government; harsh; not mild or indulgent; rigorous; as, severe criticism; severe punishment.
(superl.) Rigidly methodical, or adherent to rule or principle; exactly conformed to a standard; not allowing or employing unneccessary ornament, amplification, etc.; strict; -- said of style, argument, etc.
(superl.) Sharp; afflictive; distressing; violent; extreme; as, severe pain, anguish, fortune; severe cold.
(superl.) Difficult to be endured; exact; critical; rigorous; as, a severe test.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(3) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(4) The main clinical features pertaining to the concept of the "psycho-organic syndrome" (POS) were investigated in a sample of children who suffered from severe craniocerebral trauma.
(5) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(6) Collins said she asked Sullivan several questions, including who the women were.
(7) Single-case experimental designs are presented and discussed from several points of view: Historical antecedents, assessment of the dependent variable, internal and external validity and pre-experimental vs experimental single-case designs.
(8) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(9) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
(10) An “out” vote would severely disrupt our lives, in an economic sense and a private sense.
(11) No consistent relationship could be found between the time interval from SAH to operation and the severity of vasospasm.
(12) Also we found that the lipid deposition in the glomeruli of patients with Alagille syndrome is related to an abnormal lipid metabolism, which is the consequence of severe cholestasis.
(13) Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection.
(14) Concentrations of several gastrointestinal hormonal peptides were measured in lymph from the cisterna chyli and in arterial plasma; in healthy, conscious pigs during ingestion of a meal.
(15) In addition to the changes associated with blood group A, we also found a decrease in sugar content, alterations in other antigens, and changes in the levels of several glycosyltransferases in cancerous tissues.
(16) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(17) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
(18) After a discussion of the therapeutic relationship, several coping strategies which have been used successfully by many women are described and therapeutic applications are offered.
(19) To clarify the functional roles of His40, Glu58, and His92, we analyzed the consequences of several amino acid substitutions (His40Ala, His40Lys, His40Asp, Glu58Ala, Glu58Gln, and His92Gln) on the kinetics of GpC transesterification.
(20) Moreover, in DCVC-treated cells the mitochondria could not be stained with rhodamine-123, indicating severe mitochondrial damage and loss of membrane potential.