(superl.) Not easily penetrated, cut, or separated into parts; not yielding to pressure; firm; solid; compact; -- applied to material bodies, and opposed to soft; as, hard wood; hard flesh; a hard apple.
(superl.) Difficult, mentally or judicially; not easily apprehended, decided, or resolved; as a hard problem.
(superl.) Difficult to accomplish; full of obstacles; laborious; fatiguing; arduous; as, a hard task; a disease hard to cure.
(superl.) Difficult to resist or control; powerful.
(superl.) Difficult to bear or endure; not easy to put up with or consent to; hence, severe; rigorous; oppressive; distressing; unjust; grasping; as, a hard lot; hard times; hard fare; a hard winter; hard conditions or terms.
(superl.) Difficult to please or influence; stern; unyielding; obdurate; unsympathetic; unfeeling; cruel; as, a hard master; a hard heart; hard words; a hard character.
(superl.) Not easy or agreeable to the taste; stiff; rigid; ungraceful; repelling; as, a hard style.
(superl.) Rough; acid; sour, as liquors; as, hard cider.
(superl.) Abrupt or explosive in utterance; not aspirated, sibilated, or pronounced with a gradual change of the organs from one position to another; -- said of certain consonants, as c in came, and g in go, as distinguished from the same letters in center, general, etc.
(superl.) Wanting softness or smoothness of utterance; harsh; as, a hard tone.
(superl.) Rigid in the drawing or distribution of the figures; formal; lacking grace of composition.
(superl.) Having disagreeable and abrupt contrasts in the coloring or light and shade.
(adv.) With pressure; with urgency; hence, diligently; earnestly.
(adv.) With difficulty; as, the vehicle moves hard.
(adv.) Uneasily; vexatiously; slowly.
(adv.) So as to raise difficulties.
(adv.) With tension or strain of the powers; violently; with force; tempestuously; vehemently; vigorously; energetically; as, to press, to blow, to rain hard; hence, rapidly; as, to run hard.
(adv.) Close or near.
(v. t.) To harden; to make hard.
(n.) A ford or passage across a river or swamp.
Example Sentences:
(1) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
(2) Sierra Leone is one of the three West Africa nations hit hard by an Ebola epidemic this year.
(3) Topical and systemic antibiotic therapy is common in dermatology, yet it is hard to find a rationale for a particular route in some diseases.
(4) Given Australia’s number one position as the worst carbon emitter per capita among major western nations it seems hardly surprising that islanders from Fiji, Samoa, Vanuatu and other small island developing states have been turning to Australia with growing exasperation demanding the country demonstrate an appropriate response and responsibility.
(5) They had learned through hard experience what Frederick Douglass once taught -- that freedom is not given, it must be won, through struggle and discipline, persistence and faith.
(6) In 60 rhesus monkeys with experimental renovascular malignant arterial hypertension (25 one-kidney and 35 two-kidney model animals), we studied the so-called 'hard exudates' or white retinal deposits in detail (by ophthalmoscopy, and stereoscopic color fundus photography and fluorescein fundus angiography, on long-term follow-up).
(7) It is a moment to be grateful for what remains of Labour's hard left: an amendment to scrap the cap was at least tabled by John McDonnell and Jeremy Corbyn but stood no chance.
(8) She stopped working only when the pain made it hard for her to get to work.
(9) He was reclusive, I know that, and he was often given a hard time for it.
(10) This defeat, though, is hardly a good calling card for the main job.
(11) Since this test is easily performed and hardly stresses the patient, it should routinely be the initial one for the diagnosis of renal osteopathy.
(12) Never become so enamored of your own smarts that you stop signing up for life’s hard classes.
(13) But I don't wish to be too hard on the judge for not taking that view.
(14) Our campaign has been going for some time and each step in our progress has been hard won, by campaigners paid and volunteer alike.
(15) I am rooting hard for you.” Ronald Reagan simply told his former vice-president Bush: “Don’t let the turkeys get you down.” By 10.30am Michelle Obama and Melania Trump will join the outgoing and incoming presidents in a presidential limousine to drive to the Capitol.
(16) All the same, it's hard to approach the school, which charges nearly £28,000 for boarders and nearly £19,000 for day girls and is sometimes called "the girls' Eton", without a few prejudices.
(17) Governmental officials as well as medical scientists in Taiwan have worked hard in recent years to develop and to implement various measures, such as prenatal diagnosis and neonatal screening, to lower the incidence of hereditary diseases and mental retardation in the population.
(18) Cooper, who was briefly a social worker in Los Angeles, also suggests working hard to build a rapport with colleagues in hotdesking situations.
(19) Critics of wind power peddle the same old myths about investment in new energy sources adding to families' fuel bills , preferring to pick a fight with people concerned about the environment, than stand up to vested interests in the energy industry, for the hard-pressed families and pensioners being ripped off by the energy giants.
(20) The spirit is great here, the players work very hard, we kept the belief when we were in third place and now we are here.
Spore
Definition:
(n.) One of the minute grains in flowerless plants, which are analogous to seeds, as serving to reproduce the species.
(n.) An embryo sac or embryonal vesicle in the ovules of flowering plants.
(n.) A minute grain or germ; a small, round or ovoid body, formed in certain organisms, and by germination giving rise to a new organism; as, the reproductive spores of bacteria, etc.
(n.) One of the parts formed by fission in certain Protozoa. See Spore formation, belw.
Example Sentences:
(1) After absorption of labeled glucose, two pools of trehalose are found in dormant spores, one of which is extractable without breaking the spores, and the other, only after the spores are disintegrated.
(2) The dose response initially resembled that described by Scholer (1959) in which one million spores killed the majority of mice.
(3) Abnormal synaptonemal complexes were seen in all 19 crosses of N. crassa and N. intermedia that were examined, including matings between standard laboratory strains, inversions, Spore killers, and strains collected from nature.
(4) The mutant spores are pleomorphic and differ both in shape and size from the wild-type spores.
(5) The results presented here substantiate the hypothesis that in S. cerevisiae trehalose supplies energy during dormancy of the spores and not during the germination process.
(6) The fungicidal activity of six rabbit neutrophil cationic peptides (NP) against resting (dormant) spores, preincubated (swollen) spores, and hyphae of Aspergillus fumigatus and Rhizopus oryzae was examined.
(7) In the electron microscope large aggregates of beta glycogen particles were seen in the cytoplasm of sporoplasm cells in mature spores.
(8) The spore germination was synchronized by selection of the spores of the definite size and maintenance at a temperature of 0 degrees.
(9) GAD activity appeared in mutant spores after germination and increased to levels comparable to parent spores after 9 min of germination.
(10) The Ca++-form and H+-form spores of Clostridium botulinum 33A were investigated in vivo with respect to their water sorption and heat-resistance characteristics.
(11) Salt concentrations slightly lower than those providing inhibition tended to extend spore outgrowth time at low temperatures.
(12) The AL spores and the GN spores were morphologically distinct.
(13) Studies demonstrated the fact that there are present within the malignant cell and in the immediate area bacterial spores arising from one of several varieties of plant bacteria.
(14) The stages observed were diplokaryotic cells, sporogonial plasmodia, unikaryotic sporoblasts, and spores.
(15) The rod-shaped organism was motile, did not form spores, and had a gram-negative wall structure.
(16) Numerous factors influenced its activity: method of spore production, inherent spore resistance characteristics, alkalination, storage time and storage temperature.
(17) The inoculum level of infected spores in nutrient broth-yeast extract-glucose medium affected the transducing efficiency of SP-10 in lysates of these cultures.
(18) It can be dissociated from the spores using divalent metal chelators and will reassemble on the spores in the presence of calcium.
(19) Stable messenger ribonucleic acid (mRNA) was shown to be involved in both enterotoxin synthesis and synthesis of other spore coat proteins in Clostridium perfringens.
(20) Effects of alpha- or beta-D-glucose on the respiration of germinated spores (only germinated spores not including swollen spores and elongated spores) of Bacillus subtilis and B. megaterium were studied.