(n.) To unite or knit together confusedly; to interweave or interlock, as threads, so as to make it difficult to unravel the knot; to entangle; to ravel.
(n.) To involve; to insnare; to entrap; as, to be tangled in lies.
(v. i.) To be entangled or united confusedly; to get in a tangle.
(n.) Any large blackish seaweed, especially the Laminaria saccharina. See Kelp.
(v.) A knot of threads, or other thing, united confusedly, or so interwoven as not to be easily disengaged; a snarl; as, hair or yarn in tangles; a tangle of vines and briers. Used also figuratively.
(v.) An instrument consisting essentially of an iron bar to which are attached swabs, or bundles of frayed rope, or other similar substances, -- used to capture starfishes, sea urchins, and other similar creatures living at the bottom of the sea.
Example Sentences:
(1) The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy.
(2) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(3) Although a trend was observed for TMA-DPH mobility to parallel histopathologic severity in hippocampal specimens, the biophysical changes did not appear to reflect a loss of neuronal membranes relative to glial membranes or the presence of senile plaques or neurofibrillary tangles.
(4) Neurofibrillary tangles (NFT), one of the pathological hallmarks of Alzheimer's disease are observed in very high densities in the brains of former professional boxers suffering from dementia pugilistica.
(5) Elevated brain Al concentrations, especially in cortical regions, were associated with behavioral changes and the development of neurofibrillary tangles (NFTs).
(6) The smoky density of the mackerel was nicely offset by the pointed black olive tapenade and the fresh, zingy flavours present in little tangles of tomato, shallot, red pepper and spring onion, a layer of pea shoots and red chard, and the generous dressing of grassy olive oil.
(7) Changes were more severe in white matter close to cortical areas with a great density of neurofibrillary tangles.
(8) There is a tangled web between Salazar, Nike, Farah and the Nike Oregon Project on one hand, and the British Athletics performance director, Neil Black, and head of endurance, Barry Fudge, on the other.
(9) Whereas cortical senile plaque count did not distinguish well between demented and nondemented subjects, every subject with numerous cortical neurofibrillary tangles was demented.
(10) Clinical symptoms of amnesia appear when amyloid induces neighbouring neuritic alterations: paired helical filaments and distant neuronal body lesions: neurofibrillary tangles.
(11) Staggerer cerebellar cortex exhibits the greatest fluorescence with most terminals appearing as matted tangles adjacent cell bodies.
(12) Tangle-free neurons in both diseased and control brains showed weak to absent intracytoplasmic immunoreactivity.
(13) But tangled up in its visions of thousands of new “starter homes” – 5,000 more of which were promised on Monday, when the government said it was going to directly commission housebuilding on five sites in the south of England – are an array of drastic measures aimed at what remains of England’s council homes.
(14) The capacity for protein synthesis in tangled cells appears, therefore, to be progressively decreased with accumulation of tangle, whereas that for oxidative metabolism is maintained and lysosomal activity, perhaps, increased.
(15) On electron microscopy the normal lamellar pattern made up of orientated collagen fibrils all about 80 nm diameter is replaced by a random tangled pattern of much thinner irregularly curved fibrils, some as thin as 5nm.
(16) Eight brains failed to reveal considerable numbers of neuritic plaques, neurofibrillary tangles, and neuropil threads, but these brains showed the presence of abnormal and intensely argyrophilic grains loosely scattered throughout the neuropil.
(17) N-Terminal and C-terminal domains of tau were found to be present in tangles in situ.
(18) The neuropathological lesions were assessed using a fluorescent stain for neuritic plaques and neurofibrillary tangles.
(19) However, increased knowledge concerning macromolecular abnormalities in amyloid containing plaques and neurofibrillary tangles makes the outlook for a diagnostic test for AD on CSF promising.
(20) The trial, originally expected to be staid, has exposed severe dysfunction within Bo's family and detailed the complicated tangle of allegiances and affairs that led to his downfall .
Tingle
Definition:
(v. i.) To feel a kind of thrilling sensation, as in hearing a shrill sound.
(v. i.) To feel a sharp, thrilling pain.
(v. i.) To have, or to cause, a sharp, thrilling sensation, or a slight pricking sensation.
Example Sentences:
(1) Symptoms include numbness, tingling and pain in the anterolateral thigh.
(2) There is a reason for this and it is not merely the deeply ingrained tribal loyalty of a boy who still remembers the thrill of his first visit to the Stretford End or the tingle of excitement when offered a job as a paperboy by a former United star (in those days retired footballers had to work for a living).
(3) A spine-tingling roar rolled off the Kop after an eighth consecutive league win lifted Liverpool above Manchester City and Chelsea with perfect timing.
(4) The patient developed subacute symptoms over a 1-month period consisting of progressive pain, tingling, and weakness of the lower extremities.
(5) But I reckon Laura Tingle is dead right on the substantive challenge - the statement just shows the country can no longer coast.
(6) During the study, patients were asked about subjective neurologic symptoms such as tingling and numbness.
(7) Following routine inferior alveolar nerve block anesthesia, time is allowed for subjective signs of "tingling" of the lower lip.
(8) Similarly, the prevalence of numbness and tingling in the hands and fingers in the three exposure groups was 84%, 50%, and 17%.
(9) Side-effects with delmopinol were transient tingling and numbness of the tongue in some subjects.
(10) Another agent was benzocaine, a local anaesthetic used by dentists that produces a tingling sensation in the nose akin to that produced by cocaine.
(11) Among the exposed workers, the members of paediatric surgical staffs reported a higher rate of neurological complaints (tingling, numbness, cramps) and tiredness than the members of the other surgical staffs.
(12) A 62-year-old woman was admitted to our hospital because of tingling numbness in the trunk and upper extremities.
(13) Complaints of weakness and tingling in hands and feet, together with low-grade changes in nerve conduction, suggest the possible influence of agents with a neurotoxic esterase-type activity independent of cholinesterase activity.
(14) A good answer on hot flushes and "irritability, anxiety, depression" was obtained by Trazodone, while Veralipride showed to be more active on all neurovegetative symptoms (hot flushes, sweatings, tinglings, palpitations, astenia).
(15) The sensory changes include burning pain, numbness, tingling, and loss of sensation, while the motor changes range from weakness to complete paralysis.
(16) The commonest symptoms were numbness or tingling in the legs and feet and gait disturbance.
(17) The most common sensation was a numbness and tingling in the ipsilateral arm when the chest was being treated.
(18) The pain intensified and numbness, tingling and paraesthesia developed over 24 hours.
(19) The academic Ross Garnaut, who advised the former Labor government about climate policy, responded to a call for concrete ideas from participants from the summit moderator, Australian Financial Review journalist Laura Tingle, by suggesting Australia could adopt an economy-wide carbon price and use the revenue raised to repair the budget deficit.
(20) With subcutaneous sumatriptan (4-8 mg) similar events were observed, but certain distinctive symptoms variously described as heaviness, pressure sensation, tingling, feelings of heat or warmth, were more common and affected various parts of the body.